September 10th 2024
In this article, we review some key considerations for chromatographic technique selection and method development across the full drug process.
Using Robotic Automation to Enhance Standardization and Traceability in Clinical Diagnostics
June 6th 2023At ASMS 2023, Tabitha Hambidge of LGC presented a novel method for automating the certification of reference materials with the help of double exact matching isotope dilution mass spectrometry (DEM-IDMS).
LC–MS Methods Evaluate PFAS and Lipidomic Changes of Lettuce and Peanuts in Contaminated Soil
June 6th 2023In a talk at ASMS 2023, Rebecca L. Beres of the University of North Carolina at Chapel Hill focused on two types of analysis methods: liquid chromatography coupled to tandem mass spectrometry (LC–MS/MS) and a liquid chromatography, ion mobility spectrometry, and mass spectrometry (LC–IMS-MS) platform.
A Standardized 2D-LC Screening Platform for Peak Purity Determination in Pharmaceutical Analysis
June 1st 2023This study suggests a 2D-LC screening method to evaluate peak purity and ensure specificity in pharmaceutical analysis, thereby promoting the safe production of medicines by detecting active pharmaceutical ingredients (API) and related substances.
ASMS 2023 Will Host its Closing Event at the Houston Museum of Natural Science
May 26th 2023ASMS will conclude its conference at the Houston Museum of Natural Science (HMNS) on Thursday June 8th, from 7:00 to 10:00 pm. The HMNS is known for their paleontology display, giving attendees the opportunity to embark on a one-of-a-kind prehistoric journey while socializing with friends and colleagues.
New Procedures Enhance Quality Control for Large-Scale Plasma Proteomics Analyses
May 24th 2023A recent study has introduced comprehensive quality control procedures for large-scale plasma proteomics analyses. The research provides valuable insights into optimizing performance, enhancing reproducibility, and ensuring quantitative accuracy in proteomics investigations.
New Technique Reveals Hidden Structures of Lipid A with Multiple Glycosylation Sites
May 24th 2023A new tandem mass spectrometry technique has been developed for the rapid determination of complex lipid A structures, including novel variations from arctic bacterioplankton. This study enhances our understanding of bacterial adaptations and paves the way for the development of targeted therapies and antimicrobial agents.
New Analytical Method Enables Multi-Class Analysis of Pesticides in Corn Products
May 23rd 2023A new study introduces a comprehensive two-dimensional liquid chromatography coupled with tandem mass spectrometry (2D-LC–MS/MS) method for the analysis of 112 pesticides in corn-based products. The method exhibits high precision, lower limit of quantification values, and successful detection of trace levels of pesticides in real samples, offering promise for the analysis of complex matrices.
Ink Source Prediction and Assessment Made Possible by Mass Spectrometry
May 22nd 2023Scientists have developed a new method for predicting and assessing the source of black inks using direct analysis in real-time mass spectrometry. By applying dimensionality reduction techniques and likelihood ratio analysis, the researchers achieved high accuracy in identifying ink sources, demonstrating the potential of this approach in forensic ink analysis.