
Latest from LCGC International
15 days ago
Gulf Coast Conference 2026 PreviewLatest Content

Keeping Pace With PFAS Regulation: Analytical Strategies for Food Testing Laboratories

Conversations with Michael Dong: Why 2.1-mm i.d. Columns Are Preferred for Pharmaceutical Quality Control

UHPLC–QTOF-MS Tracks Fats Behind Soymilk's Odor

LC–MS/MS Reveals Metabolic Shifts After Ebola

Limits of Food Authentication: A Separation Science Approach to Maximum Tolerable Levels

Shorts










Podcasts
Videos
All Content

Franz Berthiller (BOKU University, Austria) discusses a multilaboratory study that used retention index markers to align mycotoxin liquid chromatography–mass spectrometry (LC–MS) data.

A QuEChERS/ultrahigh-performance liquid chromatography and high-resolution mass spectrometry (UHPLC-HRMS) method tracks 23 plant toxins in cereals and spices. Michele Suman discusses the method with LCGC International.

Gas chromatography-mass spectrometry (GC-MS) study links 110 scent compounds to cinnamon variety and origin.

Affinity chromatography-purified viral protein powers a new FAdV-8b test for chickens.

AI/ML Now: Bayesian Optimization and Automation for siRNA Method Development (Part Two)
Ed Ahearne highlights the benefits of ML-driven chromatography for the development of biopharmaceutical products

In this sixth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor compares the chromatographic properties of acetonitrile and methanol.

A three-year study of medical students and doctors in training tracked burnout symptoms alongside inflammation markers and morning cortisol and cortisone levels in saliva, measured by liquid chromatography–tandem mass spectrometry (LC–MS/MS), to better understand the biology of burnout.

AI/ML Now: Bayesian Optimization and Automation for siRNA Method Development (Part One)
Ed Ahearne combined automation, machine learning, and Bayesian optimization to speed up method development for siRNA medicines.

Data-independent acquisition (DIA) liquid chromatography-tandem mass spectrometry (LC–MS/MS) reveals shared and site-specific proteins across the thighbone.

Laura Righetti explains why quantification, not instrumentation, still keeps mass spectrometry imaging (MSI) out of routine food safety testing.

Large language models help chromatographers build LC pressure troubleshooting apps in hours.

Magnetic molecularly imprinted polymer extraction with liquid chromatography-high resolution mass spectrometry (LC–HRMS) finds patulin in store-bought juice.

LC–MS/MS Tracks Drugs in Australian Wastewater
Richard Bade and Malcolm McLeod explain to LCGC International how liquid chromatography-tandem mass spectrometry (LC-MS/MS) detects drug trends in wastewater.

In this fifth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor discusses how to overcome challenges with reversed-phase chromatography in drug analysis.

Liquid chromatography–tandem mass spectrometry (LC–MS/MS) and microbiome data reveal kidney markers of diabetic disease.























