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Low-pressure gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS) quantifies 37 volatile PFAS in food packaging in 8 minutes.

Melissa Dunkle, senior research scientist at Dow Benelux BV, The Netherlands, discusses the revival of interest in pyrolysis gas chromatography.

Jie Du of Cardinal Health discusses with LCGC International how switching from reversed-phase to hydrophilic interaction liquid chromatography (HILIC) can unmask a hidden excipient artifact mistaken for a true leachable.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS reveals antibiotics, PFAS, and toxic metals in cat kibble.

This week, Chromatography Online featured conversations from ASMS 2026 on untargeted MS/MS quantitation, RPLC-HRMS analysis of PLGA copolymers, and AI/ML predictions for non-targeted LC–ESI–HRMS workflows, alongside expert debate on harmonizing PFAS analytical methods and a sensor GC study examining whether water chasers affect alcohol metabolism.

Atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry (AP-MALDI-MS screens black pepper for fraud with minimal preparation.

Sheher Mohsin and Jeremy Koemel explore where machine learning and predictive CCS could transform PFAS identification, and what's holding it back.

Siuzdak argues the field must correct AI-fueled “phantom metabolites” before trusting predictive models, favoring experimentally grounded measurement.

The panel weighs non-targeted screening against total PFAS measurement to catch the compounds routine targeted methods may miss entirely.

Shimadzu's new TOC-1000e S continuously monitors ultrapure water for chip and precision manufacturing.

Gas chromatography-mass spectrometry (GC-MS) identifies compounds in essential oils that fight cucumber mildew.

Sheher Mohsin and Jeremy Koemel identify the biggest bottlenecks in non-targeted PFAS workflows, from CCS libraries to human review.

The panelists debate how to harmonize PFAS methods across a rapidly expanding, poorly standardized universe of compounds.