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Two-dimensional gas chromatography (2D- GC) identifies 88 sulfur compounds shaping the key aromas of soy sauce flavor Baijiu.

The panel unpacks the defining challenge of PFAS analysis: a chemical class so vast and diverse it pushes current methods to their limits.

Jim Grinias from Rowan University, NJ, USA highlights advances in miniaturized capillary LC–MS that simplify system setup and improve ease of use. He also discusses low-flow challenges and how integrated components can enhance performance and reproducibility.

Nominate a colleague for the 2027 LCGC Emerging Leader in Chromatography Award!

Nominate a colleague for the 2027 LCGC Lifetime Achievement in Chromatography Award!

High-performance liquid chromatography (HPLC) reveals how melanoma vesicles suppress immunity, informing immunotherapy response tracking.

In this month's LCGC Blog, Caitlin Cain from the University of Virginia examines whether technological advances in chromatography—particularly the adoption of big data, artificial intelligence (AI), and machine learning (ML)—are reducing the emphasis on the fundamental chromatographic theory that is key to understanding the technique.

In the third of this four-part series, Yifan Liu of Northeastern University (Boston, MA) discusses the a need for dedicated LT-ZIC-HILIC retention time library for metabolic research.

Jonathan Maurer from the University of Geneva, Switzerland describes using HILIC for oligonucleotide analysis in practice and the role of HILIC for other biopharmaceutical applications.

Gas chromatography (GC) measures volatile sulfur compounds (VSCs) in breath samples to assess remote halitosis diagnosis reliability.

Ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) identifies phenolic compounds driving honey's bioactive properties

In the second of this four-part series, Yifan Liu of Northeastern University (Boston, MA) discusses the biggest bottlenecks in untargeted metabolomics right now.

Wallman argues proteomics is moving from niche tool to high-throughput platform core, with the greatest untapped potential in covalent drug programs and targeted protein degradation.