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LC–HRMS and Magnetic Traps Detect Patulin in Apple Juice

Chromatography Tracks Drugs in Australian Wastewater

Conversations with Michael Dong: Overcoming Challenges with Reversed-Phase Chromatography in Drug Analysis

LC–MS/MS Finds Diabetic Kidney Disease Markers

UHPLC-MS/MS Tracks Maresin1 in Heatstroke Hearts

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This week on Chromatography Online, leading experts shared practical insights with LCGC International on sustainable affinity methods, siRNA impurity profiling, nontarget screening, peptide tech transfer, and AI in separation science.

Liquid chromatography–mass spectrometry (LC–MS) was used to determine if there is a link between artificial sweeteners and breast cancer.

Chiral gas chromatography–mass spectrometry (GC–MS) shows how heat and storage alter linalool in blueberry juice.

Anneli Kruve reports that toxicity predictions from MS2-derived molecular fingerprints outperform spectral-similarity methods in nontarget screening of food.

In this fourth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor explains why buffers are most often used in Mobile Phase A in high-pressure liquid chromatography of pharmaceuticals.

Skipping solid-phase extraction (SPE) cleanup rarely hurt liquid chromatography–tandem mass spectrometry (LC–MS/MS) plant hormone results in tomato.

The panel considers how AI and automation could reshape peptide method development, and why scientific judgment will remain essential.

Gas chromatography–mass spectrometry (GC–MS) and docking reveal A. excelsa leaf compounds that may help in cancer treatment.

Gert Desmet offers his insights on the potential benefits AI/ML could offer the separation science community in the future.

Quantitative non-targeted screening with predicted response factors is not for regulation, but can rank environmental chemicals by concentration and toxicity.

AI ML Now: Gert Desmet on the State of Artificial Intelligence and Machine Learning in Separation Science
Gert Desmet explores the current role of AI/ML in separation science.

Gas chromatography–mass spectrometry (GC–MS) reveals a four-stage polycyclic aromatic hydrocarbons (PAH) breakdown in oil sludge co-composted with manure.

This new high-performance liquid chromatography-ultraviolet (HPLC-UV) method measures glutathione and thiol levels across 12 berries.

Piotr Alvarez explains how HILIC complements reversed-phase LC for GLP-1 peptides, and why the field is moving toward MS-friendly TFA alternatives.

In this third part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor discusses the retention mechanism of hydrophobic interaction.




















