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Sheher Mohsin explains how CCS measurements add a physical confirmation layer beyond mass and retention time in PFAS analysis.

Siuzdak separates true standard-based empirical spectra from artifactual signals, warning AI trained on flawed data risks perpetuating errors.

High-performance liquid chromatography (HPLC) profiles serum N-glycan ratios to track psoriasis severity and treatment.

This week, Chromatography Online presented ASMS 2026 recaps, HILIC deep-dives, AI in drug discovery, and a public health story from GC-MS.

Gas chromatography-mass spectroscopy (GC–MS) and high-performance liquid chromatography (HPLC) reveal how stir-frying builds complex flavors stage by stage.

Gary Siuzdak explains how uMRM converts inconsistent untargeted LC–MS data into standardized MRM transitions.

In the final installment of this four-part series, Yifan Liu of Northeastern University (Boston, MA) forecasts where metabolomics will be headed in the next ten years.

James Grinias from Rowan University, New Jersey, USA, discusses sustainability and modern capillary LC systems.

Two-dimensional gas chromatography (2D- GC) identifies 88 sulfur compounds shaping the key aromas of soy sauce flavor Baijiu.

Jim Grinias from Rowan University, NJ, USA highlights advances in miniaturized capillary LC–MS that simplify system setup and improve ease of use. He also discusses low-flow challenges and how integrated components can enhance performance and reproducibility.

Nominate a colleague for the 2027 LCGC Emerging Leader in Chromatography Award!

Nominate a colleague for the 2027 LCGC Lifetime Achievement in Chromatography Award!

High-performance liquid chromatography (HPLC) reveals how melanoma vesicles suppress immunity, informing immunotherapy response tracking.