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Exact mass, isotopic distribution, and MS/MS library matching are used together to differentiate PFAS hits from sulfur-rich food compounds that share a similar mass defect range.

Ion-exchange chromatography (IEC) revealed tree species-driven differences in soil carbon and microbial life.

This week, Chromatography Online compiled peer-reviewed research, expert interviews, and news articles spanning chromatography and spectrometry in food analysis.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) revealed vitamin D deficiency strongly linked to childhood obesity.

Antonio Ferracane addresses regulator concerns about cleanup-free PAH methods, noting cleanup isn't mandatory if matrix validation proves reliable.

The approach remains non-targeted by prioritizing PFAS-like ions in the first DDA pass; the tunable mass tolerance window can be adjusted to capture structurally unusual PFAS subclasses.

Christine Fisher describes her method using mass defect filtering at the data acquisition stage to improve non-targeted PFAS detection in complex food matrices.

Headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) combined with machine learning accurately detected fruit juice adulteration.

Blood markers reliably shifted toward healthy diet patterns after counseling.

Color imaging and high-performance liquid chromatography (HPLC) reliably predicted pigment levels in carrots.

Hydrophilic interaction chromatography-mass spectrometry (HILIC-MS) profiling tied a senescence gene region to chlorophyll loss and seed protein in sunflowers.

Antonio Ferracane discusses moving to minimal sample preparation for PAH analysis, and why matrix-matched calibration can replace cleanup steps.

Gas chromatography-mass spectrometry (GC-MS) revealed exercise-driven metabolic reprogramming supporting neurogenesis.