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Katelynn Perrault Uptmor of William & Mary
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Building a Successful Career in Chromatography
a day ago
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Katelynn A. Perrault Uptmor
The Future is 3D
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The Future is 3D
6 days ago
by
Bo Zhang
The History of Slalom Chromatography
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The History of Slalom Chromatography
8 days ago
by
Fabrice Gritti
What are NADES? Making Science Sustainable
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What are NADES? Making Science Sustainable
12 days ago
by
Kate Jones
How Green Solvents are Revolutionizing Food Safety Analysis
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How Green Solvents are Revolutionizing Food Safety Analysis
14 days ago
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Kate Jones
Addressing Persistent, Mobile, and Toxic Compounds
0:40
Addressing Persistent, Mobile, and Toxic Compounds
20 days ago
by
Kate Jones
Tackling Complex Molecules in the Lab
0:37
Tackling Complex Molecules in the Lab
a month ago
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Kate Jones
Future Trends in the Laboratory
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Future Trends in the Laboratory
a month ago
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Kate Jones
Key Application Areas for 2026
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Key Application Areas for 2026
a month ago
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Kate Jones
The Future of Column Technology
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The Future of Column Technology
a month ago
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Kate Jones

The Column December Issue

A Look at the Latest Applications, Articles, and Interviews from the World of Chromatography

The Column December Issue

Challenges and Solutions in Oligonucleotide Analysis

An Overview of LC Methods and Applications

Challenges and Solutions in Oligonucleotide Analysis

LCGC International November/December Issue

Read the Latest Cutting-Edge Articles from LCGC

LCGC International November/December Issue

The Present and Future of Automation in Analytical Laboratories

Where Are We Heading?

The Present and Future of Automation in Analytical Laboratories

Chromatography Basics

Mastering Theoretical Plates for Better Separations

Chromatography Basics

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A recent study evaluated the anticancer potential of Israeli black scorpion venom (SFV) against colorectal cancer (CRC) using integrated biochemical, computational, and biological approaches. SFV components were characterized by gel electrophoresis, high-performance liquid chromatography (HPLC), and ultraviolet–visible (UV-vis) spectrometry, followed by in silico docking against CRC- and apoptosis-related targets.

Applying UHPLC–quadrupole-orbital trap MS–based untargeted metabolomics to evaluate psychrotrophic lactic acid bacteria as kimchi starters revealed strain-specific suppression of pathogen metabolic pathways, linking enhanced low-temperature antimicrobial performance to distinct metabolic inhibition mechanisms relevant for improving microbial safety in fermented foods.

A joint study between William & Mary (Williamsburg, Virginia) and James Madison University (Harrisonburg, Virginia) analyzed volatile organic compounds (VOCs) from commercially produced and locally sourced kombucha products using gas chromatography–time-of-flight mass spectrometry and flame ionization detection (GC-TOF-MS/FID) and comprehensive two-dimensional gas chromatography coupled with TOF-MS and FID (GC×GC-TOF-MS/FID). LCGC International spoke with Sarah Foster, lead author of the paper resulting from this study, about the team’s findings and the key takeaways from this study.

The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon) has served as a major international meeting for analytical scientists across academia, industry, and government laboratories for more than 75 years. Pittcon 2026 will take place March 7–11, 2026, at the Henry B. González Convention Center in San Antonio, Texas, under the conference theme The Scientific Frontier.

Researchers compared leaf and in vitro callus extracts of Eucalyptus camaldulensis using liquid chromatography–mass spectrometry (LC–MS) and gas chromatography–mass spectrometry (GC–MS) to assess phytochemical composition and bioactivity. Callus extracts contained a greater diversity and higher abundance of secondary metabolites, including flavonoids and key volatiles such as 1,8-cineole, α-terpineol, and sabinene. Bioassays showed superior anti-inflammatory and antioxidant activity in callus-derived oils, surpassing standard drugs, highlighting tissue culture as a powerful tool for enhancing natural therapeutic compounds.

Malaria causes nearly one million deaths annually, prompting the search for new vector-control strategies. Inspired by chimpanzee behavior in Uganda’s Kibale National Park, researchers analyzed essential oils from four local tree species—three used for chimpanzee nesting—using gas chromatography-mass spectrometry (GC–MS). A mixture of key compounds showed toxic and irritant effects on malaria-carrying mosquitoes, suggesting chimpanzee-inspired, plant-based repellents as a sustainable approach to the prevention of the disease.