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"One-Shot" Solutions for Preparative Chiral Sub/Supercritical Fluid Chromatography Using Chiroptical Detection
A new “one-shot” strategy for preparative chiral supercritical fluid chromatography (SFC) offers fast and effective approach to obtain and characterize individual enantiomers.

SFC delivers measurable cycle-time and solvent-use gains beyond chiral work, spanning biopharma and anti-doping applications, experts say.

SFC Europe 2026 brings global experts to Basel for courses, scientific talks, workshops, and insights into greener separation technologies.

Karine Faure discusses how SFC with alternative solvents could offer a more sustainable path forward for liquid chromatography separations.

Daniel W. Armstrong explains how SFC confirmed mirror-image ruthenium photosensitiz-ers perform identically against melanoma cells.

Kevin Schug explains how surrogate optimization streamlines SFE–SFC–MS method development, achieving R² values up to 0.97 while boosting sensitivity by 15%

LCGC International spoke to Cristian Reale about an eco-friendly SFC-PDA method that rapidly measures furocoumarins in Citrus essential oils.

In preparative chiral supercritical fluid chromatography (SFC), adding 2.5–5% water cuts retention times and narrows collection windows, boosting throughput.

Caroline West on supercritical fluid chromatography's advances, pharmaceutical applications, and sustainability.

Princeton Chromatography's Jeff Caldwell says SFC can now complete separations in 10–15 seconds.

Perception, not technology, remains the biggest barrier to supercritical fluid chromatography (SFC) adoption, says JASCO's Tom DePhillipo.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) shows sunlight, not demographics, drives vitamin D in zoo rhinos.

Part 2 of this series applies IUPAC nomenclature to core gas chromatography data analysis, defining and explaining key parameters—retention time, hold-up time, peak width, retention factor, selectivity, and plate number—used to interpret and report chromatograms.

Gas chromatography-mass spectrometry (GC-MS) reveals how buried heavy oil weathers and threatens groundwater.

This week, Chromatography Online presented PFAS environmental research, ISC 2026 symposium highlights, interviews with Waters Corporation’s Erin Chambers, and health-related LC-MS studies on exercise chemistry and age-related macular degeneration treatment.















