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How can analysts resolve impurities that differ by a single mass unit? Experts discuss deamidation, racemization, HRMS, and 2D-LC for GLP-1 peptides.

"LC Troubleshooting" explores why phosphorothioate oligonucleotides (ONs) diastereomers challenge liquid chromatography.

This new high-performance liquid chromatography (HPLC) method reliably measures cholesterol adsorption in artichoke fiber.

The panel walks through confirming peptide identity–from HRMS and LC–MS/MS sequencing to amino acid analysis and D/L-isomer verification.

Malte Hübschen of the University of Duisburg-Essen (Germany) discusses an automated gas chromatography-tandem mass spectrometry (GC-MS/MS) workflow that improves phthalate detection in tricky oils with LCGC International.

Kinjal Bhatt says belonging comes from team culture, not headcount, while Ina Varfaj's goal as her lab's only woman is making sure she isn't the last.

Liquid chromatography–ion mobility spectrometry–high-resolution mass spectrometry (LC–IMS–HRMS) shows elephant seal pups carry more PFAS than their mothers do.

Gas chromatography–mass spectrometry (GC–MS) and omics profiling distinguish duck and goose foie gras composition.

This week's Chromatography Online highlights include olive waste antioxidant recovery, food and tea analysis, EV isolation, mRNA vaccine purification, perfusion chromatography for oligonucleotides, mass spectrometry in teaching and career advice from “Women in Chromatography.”

Kinjal Bhatt and Ina Varfaj call AI a chromatography equalizer only if training and access keep pace, framing the risk as implementation, not technology.

In part 1 of "Conversations with Michael Dong," LCGC column editor Michael Dong explains basic drugs and why most drugs are basic rather than acidic.

Gas chromatography–mass spectrometry (GC–MS) and liquid chromatography–mass spectrometry (LC–MS) reveal lasting brain cholesterol loss after myelin damage.

Metrohm USA's IONIC Titrator offers cloud access and a 10-inch touchscreen.

Chromatography and spectrometry were used in tandem to reveal how ultrasound boosts chicken soup flavor compounds.

Tony Edge explains how SPE optimization improves oligonucleotide LC–MS data.























