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Summary: A preview of 2026 separation science trends, from PFAS and SFC to metabolomics, next-generation HPLC columns, oligonucleotides, and ADC analysis.

Hans-Gerd Janssen explores the industry's shift from fully integrated online systems to at-line approaches.

Headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry (HS-SPME-GC-MS) links orange flavor and aroma differences to regional climate factors.

Ion chromatography ties chloride levels to heat-enhanced fingerprint clarity.

Micro-liquid chromatography-tandem mass spectrometry (LC-MS/MS) finds no cerebrospinal fluid endocannabinoid link to migraine, but rather to mood.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) shows soaking, ultrasound cut popcorn acrylamide levels by 82%.

Does high-performance liquid chromatography (HPLC) analysis show that melittin alone can't predict bee venom quality?

A worrying trend has emerged in UK higher education: the systematic erosion of deep, hands-on chromatography instruction and delivery of this key technique by non-experts, according to Tony Edge, President of The Chromatographic Society (ChromSoc). Can this trend be reversed?

LCGC International spoke to the University of Salerno’s Eduardo Maria Sommella and Danila La Gioia regarding a new hydrophilic interaction liquid chromatography-high resolution mass spectrometry (HILIC-HRMS) method which quantifies circulating analytes to help detect liver cancer.

HTC-19 Insights: Advancing HPLC–XRF for the Analysis of Brominated Flame Retardants and Other Pollutants
Gaëlle Spileers from the Separation Science Group in the Department of Organic and Macromolecular Chemistry at Ghent University, Belgium discusses developments in high performance liquid chromatography (HPLC–XRF) for the analysis of brominated flame retardants and other pollutants.

The panel closes with a shared message: define your question first, and remember every result is an estimate.

HTC-19 Insights: HPLC–XRF for Environmental Analysis — Future Developments
Gaëlle Spileers from the Separation Science Group in the Department of Organic and Macromolecular Chemistry at Ghent University, Belgium discusses developments in high performance liquid chromatography (HPLC–XRF) for the analysis of brominated flame retardants and other pollutants.

High-performance liquid chromatography (HPLC)-verified caffeine dose eased mental fatigue from nap deprivation in a recent pilot study.

Chromatography of tooth layers links prenatal pollutants to autism risk.

Frederic Lynen from the Separation Science Group in the Department of Organic and Macromolecular Chemistry at Ghent University, Belgium discusses why he worked with Gaëlle Spileers to develop a high performance liquid chromatography X-ray fluorescence (HPLC–XRF) technique to analyze brominated flame retardants and other pollutants.






















