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Measuring the small molecules that fuel cell metabolism, things like amino acids, sugar phosphates, and energy carriers, turns out to be trickier than it sounds. Victoria Pozo Garcia explains to LCGC International why hydrophilic interaction liquid chromatography (HILIC) tends to work better for these compounds than the more common reversed-phase method.

High-performance liquid chromatography (HPLC) and proton-transfer-reaction time-of-flight mass spectrometry (PTR-ToF-MS) data power AI-based grading of Baimudan white tea.

This week, Chromatography Online covered MALDI-MSI/LC-GC-MS tissue mapping, phthalate and microplastic screening, coastal pollutant analysis, vitamin D-sleep links, smartphone TLC drug detection, plus FDA 483 guidance and looks at HPLC2026 and the upcoming ISC2026 conferences.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) reveals PFAS migration into saliva from children's stuffed toys.

Analytical quality by design (AQbD) lifecycle series tackles risk-based methods

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) ties seasonal vitamin D changes to sleep timing in women.

Ultrahigh-pressure liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) study links rice pleiotropic developmental defects to tRNA modifications and organelle functions.

ISC 2026 in Prague (Sept 6–10) covers chromatography fundamentals, LC/GC/SFC, MS hyphenation, AI/ML, and omics applications, featuring three scientific tracks, industry program, and early-career researcher opportunities.

Highlights from the HPLC2026 Conference through the Lens of LC Troubleshooting
HPLC2026 highlights: four talks on liquid chromatography (LC) troubleshooting and problem prevention.

Pyrolysis gas chromatography-mass spectrometry (Py-GC–MS) quantifies microplastic exposure risks in Korean playgrounds.

Verdel Instruments' Q-2DMS upgrade kit, developed with University of Warwick researchers, brings two-dimensional mass spectrometry to standard QTOF benchtops.

Gas chromatography-tandem mass spectrometry (GC-MS/MS) reveals organochlorine pesticide and polychlorinated biphenyl pollution levels in Greek coastal sediments.

Is FDA getting tired of writing warning letters? A new draft guidance shows how companies should respond to Form 483 observations.

Smartphone thin-layer chromatography (TLC) catches tizanidine drug residue on pharmaceutical manufacturing equipment.

Gas chromatography (GC) reveals algae-fed chickens boost meat omega-3 without hurting growth.























