Mass Spectrometry

Scientists from Fudan University in Shanghai, China created a system for reducing retention-time variations in metabolomic analysis using ultrahigh-performance liquid-chromatography coupled with mass spectrometry (UPLC-MS).

A group of scientists from Xi’an, China have created a new system for analyzing cell membranes based around HALO-tag technology.

Scientists from Essen, Germany recently created a method for simultaneously analyzing fatty acids (FAs) and fatty acid methyl esters (FAMEs).

A recent study published in the Journal of Separation Science reveals how ultrahigh-performance liquid chromatography tandem mass spectrometry (UHPLC–MS/MS) could be used to detect and quantify purine metabolites.

Innovative native separation strategies coupled with native mass spectrometry techniques to characterize biopharmaceuticals close to their natural state are described.

A novel method to simultaneously characterize the capping and poly(A) tail for therapeutic mRNA in a single sample preparation workflow is described.

An interview with Reed Harris on critical quality attributes and other contemporary trends in biopharm analysis.

A novel LC–MS/MS method, with a dual ESI and APCI source using simple solvent extraction for sample preparation, was validated for analysis of 102 pesticides and 5 mycotoxins regulated by Colorado state in dried hemp.

LCGC spoke to Leandro Wang Hantao from the University of Campinas in São Paulo, Brazil, about his work investigating the influence of ion management parameters on the data produced by comprehensive gas chromatography–high-resolution mass spectrometry (GC×GC–HRMS) equipped with a fourier transform-orbital ion trap mass analyzer, and his investigation into employing channel occlusion for sample preparation in untargeted analysis in petroleomics.

Ion suppression is a known matrix effect in electrospray ionization (ESI), ambient pressure chemical ionization (APCI), and desorption electrospray ionization (DESI).

Scientists are investigating the effectiveness of different PFAS analysis techniques in aquatic environments.

Scientists from South Dakota State University and the University of Colorado School of Medicine created a system to detect traces of cyanide in blood samples using liquid chromatography–tandem mass spectrometry (LC–MS/MS).

Scientists recently used laser desorption ionization mass spectrometry (LDI-MS) to detect toxic alkaloids in traditional Chinese medicines (TCM).

Microfluidic capillary electrophoresis mass spectrometry (CE-MS) using ZipChip technology provides intact mass evaluations and efficient separation of oligonucleotides.

Agilent Technologies presents this award to industry leaders as a means of supporting them through financial aid, products, and expertise, along with recognition.

At the Eastern Analytical Symposium (EAS) in Plainsboro, NJ, Sam Heckle, an analytical chemist from CEM Corporation, presented “The Importance of Digestion Temperature on Trace Metals Analysis”, where he discussed the do’s and don’ts of heavy metal analysis meant to get optimal digestion.

For the first time, inhibitors of a cyclooxygenase isoform were found in Allium ampeloprasum L., specifically the giant or “elephant” garlic grown in the Chiloé Archipelago.

Webinar Date/Time: Mon, Dec 4, 2023 11:00 AM EST

At the Eastern Analytical Symposium (EAS) in Princeton, New Jersey, LCGC magazine sat down with John McLean of Vanderbilt University to discuss his research and career in mass spectrometry.

A group of scientists created a minireview of the versatile nature of ion mobility–mass spectrometry (IM–MS), and how the technique can be used in different scenarios.

Kennedy is a professor at the University of Michigan.

Researchers used metabolomics analysis to measure different harvest times during the whole growing period of ligustri lucidi fructus (LLF), a traditional Chinese medicinal herb.

A group of scientists from the Luxembourg Institute of Science and Technology (LIST) tested different methods of using matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) to analyze human skin cells.

To combat fraudulent sales of low-aged ginseng disguised as high-aged ginseng, scientists from Shanghai University of Traditional Chinese Medicine created machine learning models to predict the ages of ginseng samples.

Scientists from Zhejiang, China recently conducted experiments meant to properly characterize sucrose ester isomers from tobacco samples.

Webinar Date/Time: Tuesday November 28, 2023 9:30 AM EST | 2:30 PM GMT | 3:30 PM CET Wednesday, November 29, 2023 9:30 AM EST | 2:30 PM GMT | 3:30 PM CET

The Column spoke with Ilaria Belluomo from Imperial College London, UK, about her research in breath analysis. She details her work into a noninvasive breath test that can be used to detect colorectal cancer using GC–MS. She also discusses the use of SIFT-MS for the analysis of VOCs in breath.

Scientists from the University of Maryland have created a system to analyze changes in a brain’s chief circadian pacemaker.

Troubleshooting continues to evolve constantly, changing how we overcome issues such as chemical causes of peak tailing.

Gas chromatography can be used in combination with molecular spectroscopy to provide structural and quantitative information on a variety of sample types.