UHPLC

Waters Corporation and Princeton University scientists recently investigated how using elastic flow instability can improve the kinetic performance of chromatographic columns.

In a new study, scientists reflected on different advancements made in extracting, purifying, and quantifying kaempferol, a natural product present in various sources.

Here is some of the most popular content posted on LCGC International this week.

Korea Food Research Institute scientists combined QuEChERS extraction with ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC–MS/MS) to analyze vitamins D and K in yogurt.

Scientists from Henan Normal University and Yellow River Conservancy Technical Institute used UHPLC–MS/MS to characterize quaternary phosphonium compounds (QPCs) and phosphine oxides (POs) in water and solid samples.

Here are the top five articles published on LCGC International this week.

Scientists from the Institute of Environmental Assessment and Water Research developed and optimized a method for determining various pesticides in human urine.

Tianjin Centers for Disease Control and Prevention scientists used chromatography techniques to determine bisphenol analogues (BPs) in human urine.

At HPLC 2024 in Denver, Colorado, various sessions will be led by experienced scientists, covering different aspects of chromatography techniques and maximizing their effectiveness. Here is some information about tomorrow’s sessions.

Scientists from the National Veterinary Research Institute used UHPLC-MS/MS as part of a new antimicrobial detection method in edible pig tissue.

Scientists from Roche Diagnostics in Germany are testing a new liquid chromatography (LC)-based approach for advancing process analytical technology (PAT) in biopharmaceutical processing.

Scientists in France took 122 swabs from the smartphones of music festival goers to test for a variety of illicit drugs including cocaine and MDMA.

LCGC International sat down with Susana Palma of CIAD to discuss her career and work with the Females in Mass Spectrometry (FeMS) group.

In the world of liquid chromatography, innovative strides in column technology continue to take place. We are also reminded that there is always more to learn about “well-known” methodologies, and our craft is continuously influenced by important social concerns.

Governments are striving to implement policy changes towards a greater use of green technology, specifically around the generation of energy. Individuals and industrial organizations have also taken up the challenge, and now many companies are driving to significantly reduce their environmental footprint, or indeed become carbon negative within very short time frames.

This paper describes advances in column design that enable the analyst to achieve high sensitivity and efficiency when reducing the internal diameter of the column.

In this edition of The LCGC Blog, Emanuela Gionfriddo discusses the two world-class scientists and trailblazer women in separation chemistry and the awards they received at Pittcon 2024.

Tony Edge, Stephane Moreau, Carsten Paul, and Fraser McLeod discuss the latest trends and developments in LC.

How long should you perform an extraction of woodruff leaves so that you don’t end up with a harmful amount of coumarin, but still get the characteristic flavor of the finished May wine?

As opposed to targeted metabolomics which looks only at a predetermined set of metabolites or their pathways, an untargeted approach was preferred by this research team because of its unbiased yet still comprehensive nature.

The flowmeter, Testa said in a press release, was compared favorably as an alternative to more traditional flow calibration methods for HPLC pumps.

In this interview for ASMS 2024, Liusheng Huang of the University of California San Francisco discusses his upcoming presentation about performing microvolume analysis on antimalarial drugs.

Xinyi Biyan is a Chinese patent medicine with significant therapeutic effects, widely used clinically to treat acute and chronic rhinitis or allergic rhinitis.

Scientists from Changchun University of Chinese Medicine used UHPLC-Q-Orbitrap-MS/MS analysis to identify the active compounds in TongFu XieXia Decoction for treating intestinal obstruction.

Scientists from the Lunan Pharmaceutical Group explored the use of UHPLC-MS/MS to test the effects of Shouhui Tongbian capsules (SHTBs) on slow transit constipation (STC).

This article covers liquid chromatography columns and accessories commercially released after Pittcon 2023 through the 2024 conference.

Here are the top five articles that the editors of LCGC International published this week.

Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.

Scientists from Anhui University of Chinese Medicine in Hefei, China recently investigated the mechanisms behind what makes huachansu tablets, a type of traditional Chinese medicine (TCM), effective against liver cancer.

Here are the top five articles that the editors of LCGC International published this week.