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Analytical Instrumentation
Analytical Theory
Biological, Medical, and Clinical Analysis
Biopharmaceutical Perspectives
Biopharmaceuticals and Protein Analysis
Cannabis Analysis
Capillary Electrophoresis
Chiral Chromatography
ChromAcademy
Corporate Profiles
Data Acquisition, Handling, and Archiving
Data Analysis, Statistics, and Chemometrics
Dietary Supplements Analysis
Environmental Analysis
Field-Flow Fractionation (FFF)
Food and Beverage Analysis
Forensics, Narcotics
From the Editor
GC–MS
Gas Chromatography (GC)
HILIC
HPLC
Ion Chromatography
LCGC Interviews
LCGC TV: Gas Chromatography
LCGC TV: Hyphenated Techniques
LCGC TV: Liquid Chromatography
LCGC TV: Sample Preparation
LC–MS
Liquid Chromatography (LC/HPLC)
Market Profiles
Mass Spectrometry
Medical/Biological
Multidimensional GC
Multidimensional LC
Peer-Reviewed Articles
Pharmaceutical Analysis
Preparative-Scale Chromatography
Process Analytical Technology (PAT)
Quality Control/Quality Assurance (QA/QC)
Quality by Design (QbD)
Regulatory Standards, GLP and GMP Compliance
Sample Preparation
Size-Exclusion Chromatography (SEC)
Solid-Phase Extraction (SPE)
Supercritical Fluid Chromatography (SFC)
Supercritical Fluid Extraction (SFC)
The Next Generation
Thin Layer Chromatography
Trends
UHPLC
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Evelyn Wang

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Evelyn Wang is with Shimadzu Scientific Instruments in Columbia, Maryland.

Articles

Abstract scientific beakers and bunson burners. Bubbling concoctions and chemical reactions. Colorful vials of liquid. | Image Credit: © Fox Ave Designs - stock.adobe.com

An Overview of the Untargeted Analysis Using LC–MS (QTOF): Experimental Process and Design Considerations

Tiffany Liden;Evelyn Wang;Kevin A. Schug
October 1st 2023

Untargeted analysis using liquid chromatography with tandem mass spectrometry (LC–MS/MS) chemical profiling is a valuable tool, but care needs to be taken with experimental design.

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