November 12th 2024
The method of standard additions (MoSA) enables quantification of volatile impurities in condensed-phase samples, such as emulsions, for which matrix-matched calibration standards are required. The technique is, however, expensive because it requires multiple analyses of each sample.
Systematic Evaluation of HILIC Stationary Phases for MS Characterization of Oligonucleotides
Hydrophilic interaction chromatography–mass spectrometry (HILIC-MS) offers a flexible and efficient alternative to ion-pairing reversed-phase liquid chromatography (IP-RPLC) for oligonucleotide analysis, with column selectivity and mobile phase pH being key factors in optimizing retention and detection.
New Algorithm Created for Detecting Volatile Organic Compounds in Air
October 9th 2024Scientists from Institut de Combustion, Aérothermique, Réactivité et Environnement (ICARE-CNRS) in Orléans, France and Chromatotec in Saint-Antoine, France recently created a new algorithm for detecting volatile organic compounds (VOCs) in ambient air.
SFE-SFC-MS Used to Analyze Transferred Plastic Additives from Laboratory Materials
September 30th 2024Supercritical fluid extraction (SFE) was combined with supercritical fluid chromatography (SFC) hyphenated to mass spectrometry (MS) to analyze plastic additives that could be transferred into the environment from laboratory gloves.
Nanospray Laser-Induced Plasma Ionization Mass Spectrometry to Analyze Persistent Organic Pollutants
September 3rd 2024Scientists from the Guangdong Academy of Sciences and the Guangdong University of Technology used nanospray laser-induced plasma ionization mass spectrometry (nLIPI-MS) to analyze broad polarity organic pollutants under ambient and open-air conditions.