September 4th 2024
Stockholm University scientists used liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) to characterize recycled textile products and detect harmful chemicals.
New Method Developed to Map Cellulose Ether Monomer Composition
May 2nd 2023A new RPLC–MS method can map the substitution degree and composition of β-glucose monomers of cellulose ethers (CEs), providing detailed compositional distributions and constitutional isomer distributions, thereby identifying compositional variation between bio-stable and non-bio-stable CEs and unexpected methylations in EHEC samples.
Using HPLC–MS and GC–MS for Improving Speed and Accuracy of Organosulfur Compound Detection
May 2nd 2023High performance liquid chromatography–mass spectrometry and gas chromatography–mass spectrometry, along with numerous extraction methods, are helping to find organosulfur compounds in food more easily, providing researchers better information about the health benefits of these substances.
Exploring Biopharmaceutical Analysis with Compact Capillary Liquid Chromatography Instrumentation
A recent trend in the design of LC instrumentation is the move towards miniaturized and portable systems.
A Novel Mass Spectrometry Paradigm to Analyze Classical and New Biotherapeutic Modalities
May 1st 2023A new fragmentation approach—tunable electron-activated dissociation (EAD) tandem mass spectrometry (MS/MS)—offers a solution to better improve the detection and characterization of impurities in lipid nanoparticles and impurities in other biopharmaceutical modalities.
An LC–MS/MS Method for the Evaluation of Intestinal Permeability in Blood Plasma
May 1st 2023A rapid and robust LC–MS/MS method for determining lactulose and rhamnose concentrations in blood plasma was used to determine intestinal permeability from blood plasma, which can help diagnose gastrointestinal diseases such as Crohn’s disease.
Demystifying Sample Preparation for Headspace Analysis Using Direct Injection Mass Spectrometry
May 1st 2023Direct-injection mass spectrometry (DIMS) and gas chromatography (GC) approaches have some significant differences that are pertinent when analyzing volatile organic compounds (VOCs). We explain.
Analysis of PFAS in Locally Acquired Food Containers
May 1st 2023The combination of an untargeted approach using ultrahigh pressure liquid chromatography–quadrupole time-of-flight mass spectrometry (UHPLC–QTOF) and a targeted approach using UHPLC–tandem mass spectrometry (MS/MS) are presented as an ideal method for detecting per- and polyfluroalkyl substances (PFAS) in fast-food packaging.
LCE and LCA: Suspect Screening of Lupin-Produced Phytotoxins in Environmental Samples
April 30th 2023Selective pressurized liquid extraction and multilayer solid‑phase extraction methods are described for high‑throughput plant, soil, and water sample preparations. Optimal analytical conditions are described for the improvement of detection sensitivities and coverage. A Source Supported Suspect Screening (4S) approach is described; phytotoxins detected in the source plant were used to improve the identification of phytotoxins in soil and water.
GC✕GC–TOF-MS Helps Quantify Pesticides in Water Susceptible to Contamination
April 28th 2023Pesticides in local surface and groundwaters were purified and enriched with solid-phase extraction, then analyzed using multidimensional gas chromatography coupled to mass spectrometry, with the results compared to those found by gas chromatography–quadrupole mass spectrometry.
Advancements in High Spatial Resolution Mass Spectrometry Imaging for Spatial Metabolomics
April 28th 2023A review article describes spatial metabolomics using high spatial resolution mass spectrometry imaging (MSI), a promising technology that enables the visualization and analysis of metabolites at the cellular and subcellular levels.
ESI-MS: The Future of Single-Cell Proteomics
April 28th 2023Recent advancements in electrospray ionization mass spectrometry (ESI-MS) for single-cell proteomics are highlighted in a review article, including various separation techniques and MS instrumentation used to improve sample throughput and coverage.
New and Improved Method for Extracting α-Cellulose for Isotopic Analysis
April 26th 2023New GC–MS research suggests that the presence of hemicellulose impurities in α-cellulose extracted from land plants may compromise reliable application of the 18O/16O ratio for environmental, physiological, and metabolic studies.
The 2023 ASMS Research, PUI, and Postdoctoral Career Development Awards
April 25th 2023Every year, the American Society for Mass Spectrometry (ASMS) presents Research Awards, the Research at Primarily Undergraduate Institution (PUI) Award, and Postdoctoral Career Development Awards. This year's winners will be honored at the 2023 ASMS Conference in Houston, Texas, from June 4–8.
Carol V. Robinson Wins 2023 John B. Fenn Award for Distinguished Contribution in Mass Spectrometry
April 24th 2023Carol V. Robinson of the University of Oxford has been named the 2023 recipient of the ASMS John B. Fenn Award for Distinguished Contribution in Mass Spectrometry. Robinson will receive the award at the 2023 ASMS Conference in Houston, Texas, which takes place June 4–8.
Principles and Practical Steps to Develop Robust Reversed Phase Separations of Peptides
April 21st 2023Webinar Dates/Times: Session 1 (EU): Wednesday, May 17th, 2023 at 2pm BST | 3pm CEST | 9am EDT Session 2 (NA): Wednesday, May 17th, 2023 at 1pm EDT | 10am PDT | 6pm BST Session 3 (APAC): Thursday, May 18th, 2023 at 12pm JST | 11am CST | 11pm EDT