Claire I. Butré

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Claire I. Butré is R&D Technical Leader at Quality Assistance.

Articles

Molecule of mRNA, 3D illustration | Image Credit: © Dr_Microbe - stock.adobe.com

Multi-Attribute Monitoring of Therapeutic mRNA by Liquid Chromatography–Mass Spectrometry

Thomas Menneteau;Claire I. Butré ;Damien Mouvet;Arnaud Delobel
December 1st 2023

A novel method to simultaneously characterize the capping and poly(A) tail for therapeutic mRNA in a single sample preparation workflow is described.

LC MS system. Liquid chromatography with qTOF mass detector. Chemical laboratory, clinical analysis | Image Credit: © vladim_ka - stock.adobe.com

2D-LC–MS Approaches for the Analysis of In-Process Samples and for the Characterization of mAbs in a Regulated Environment

Claire I. Butré ;Arnaud Delobel
October 1st 2023

The methodologies demonstrated here open the way to fully compliant at-line monitoring of monoclonal antibody quality attributes.

monoclonal antibodies on a screen

New 2D-LC–MS Approaches for the Analysis of In-Process Samples and for the Characterization of mAbs in a Regulated Environment

Arnaud Delobel;Claire I. Butré
December 1st 2022

The methodologies demonstrated here open the way to fully compliant at-line monitoring of monoclonal antibody quality attributes.

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