Author
Latest:
Hyphenation of Flow-Injection Analysis with Mass Spectrometry: A Versatile and High-Throughput TechniqueA review highlighting the recent development on flow-injection analysis (FIA)–mass spectrometry (MS) to bring more attention to this effort.
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Multidimensional Separation Techniques for Characterization of BiotherapeuticsMultidimensional separations, in which two or more separation methods are coupled, are a valuable analytical tool for higher peak capacity and improved selectivity for the analysis of complex samples like biotherapeutics.
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Trouble-Free UHPLC-Like Performance Using 2 mm I.D. Monolithic Silica ColumnsTuesday, June 22, 2021 at 10am EDT | 3pm BST | 4pm CEST Leverage UHPLC-like performance using monolithic 2 mm-I.D. columns. Increase lab efficiency with trouble-free, fast, and efficient HPLC of challenging and matrix-rich samples.
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The Use of Mass-Spectrometry-Based Proteomics for Reliable Detection and Identification of Pathogens as Illustrated by the Study of Bee Colony Collapse DisorderA study of colony collapse disorder in honey bees illustrates how mass spectrometry–based proteomics techniques can be used to to identify pathogens without any prior knowledge of what is contained in the sample.
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Astaxanthin from Shrimp By-products for Active Packaging SystemsThe two year international project "Preparation of active packaging with antioxidant and antimicrobial activity based on astaxanthin and chitosan",1 which started in 2009, was funded by FONCYCIT (Fund for International Cooperation of Science and Technology between the European Union and Mexico).
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Theoretical Concepts and Applications of Turbulent Flow ChromatographyTurbulent flow chromatography is often used for on-line sample cleanup of biological matrices in liquid chromatography–mass spectrometry applications.
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An Accurate Mass Database for the Analysis of Pesticides and Veterinary Drugs using Liquid Chromatography-High-Resolution Mass SpectrometryHere, the process to build an accurate mass database is thoroughly described and applications are commented on.
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Gas Chromatography–Mass Spectrometry Characterization of Vegetable Oil–Derived Potent Antimicrobial AgentsUnder a suitable thermal oxidation regime, vegetable oils yield a mixture of volatile and semivolatile organics that exhibit very high antimicrobial activities against a variety of microbial species. Volatile and semivolatile products were characterized with GC–MS using electron ionization and chemical ionization. The thermal oxidation of vegetable oils resulted in the formation of an array of short and medium-chain acids, aldehydes, and ketones that act synergistically to yield a potent antimicrobial disinfectant.
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Incorporating HPLC as a Multi-Attribute Characterization Technology for Next-Generation Drug DevelopmentThis paper provides an overview of some current and emerging physicochemical analytical challenges associated with these sophisticated drug systems and some of the technical advances needed in chromatographic systems to enable their design, development, and manufacture.
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A Novel Approach to Measure Crop Plant Protein ExpressionCrop development to improve yield or disease resistance has been explored for centuries and the technologies to measure these improvements have subsequently become complex.
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Nontargeted, Discovery-Based Profiling of the Yeast Metabolome Using QTOF LC–MS and LC–MS-MSA discovery-based, untargeted metabolomics analysis of hundreds of yeast metabolites under robust, controlled extraction conditions followed by identification is described.
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Metal-Analyte Interactions—An Unwanted DistractionA new method to deal with the interaction of transition metals with analytes has been developed and is described.
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Optimal Separation of Polar Anionic Pesticides from Fruits and Vegetables with HPLC Column SelectivityThis article presents a new column technology that uses reversed phase separation and offers excellent peak shape, resolution, and robustness for a wide variety of food matrices.
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Toward Quantitative Imaging Mass SpectrometryThe main limitations of quantification using MALDI imaging are discussed and the different approaches used for quantitative measurement in MSI are evaluated.
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Identification of Novel Psychoactive Substances Using Hyphenated Mass Spectrometric TechniquesGas chromatography–mass spectrometry (GC–MS) and liquid chromatography–mass spectrometry (LC–MS) techniques offer advantages in separating and confirming the identity of constituents in novel psychoactive substances.
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Back-tracing Poultry Meat Chain Exposure to Rapidly Metabolized Pollutants Using Volatile Compound Metabolic Signatures in Liver TissuesIt is well established that food-producing animals are exposed to toxic micropollutants via environment and feeds, and that micropollutants entering the animals are transferred to edible tissues, thus representing a chemical human health hazard.
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Analysis of Paralytic Shellfish ToxinsThe paralytic shellfish toxins are a group of 18 secondary metabolites deposited in bivalve mollusks by dinoflagelates. Dinoflagelate blooms are seasonal, occurring during warm months.
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Astaxanthin from Shrimp By-products for Active Packaging SystemsThe two year international project "Preparation of active packaging with antioxidant and antimicrobial activity based on astaxanthin and chitosan",1 which started in 2009, was funded by FONCYCIT (Fund for International Cooperation of Science and Technology between the European Union and Mexico).
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Polar Vapor-Enhanced Separations with Planar Differential Mobility Spectrometry-Mass SpectrometryA brief historical overview of DMS, followed by a synopsis of the instrumentation, physics, and chemistry behind the separation principles
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Interactive Liquid Chromatography of Olefin-based ElastomersThe use of interactive liquid chromatography using porous graphite as a stationary phase and gradients of long chain alcohols and chlorinated aromatics to separate olefin-based elastomers according to their chemical composition is discussed.
Latest:
Astaxanthin from Shrimp By-products for Active Packaging SystemsThe two year international project "Preparation of active packaging with antioxidant and antimicrobial activity based on astaxanthin and chitosan",1 which started in 2009, was funded by FONCYCIT (Fund for International Cooperation of Science and Technology between the European Union and Mexico).
Latest:
Astaxanthin from Shrimp By-products for Active Packaging SystemsThe two year international project "Preparation of active packaging with antioxidant and antimicrobial activity based on astaxanthin and chitosan",1 which started in 2009, was funded by FONCYCIT (Fund for International Cooperation of Science and Technology between the European Union and Mexico).
Latest:
Advantages of Sequential or Bracketed Injection Methods to Improve the Chromatographic Analysis of BiotherapeuticsThis article explores three case studies where autosampler injection programs help to (i) reduce the carry-over observed for large nucleic acids during anion-exchange chromatography (AEX), (ii) reduce peak distortion and breakthrough for monoclonal antibodies (mAbs) during hydrophilic-interaction chromatography (HILIC), and (iii) facilitate dissolution of lipid nanoparticles (LNPs) so that a size-exclusion chromatography (SEC) method can be applied for ribonucleic acid (RNA) payload analysis.
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GCxGC with Fluidic Modulation on Enantioselective Oil AnalysisDescribes a novel approach for the enantioselective separation of spearmint oil incorporating a fluidic modulation system.
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Analysis of Bovine Serum Albumin (BSA) Digest on a Thermo Scientific Accucore 150-C18, NanoLC ColumnThermo Scientific Application Note
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Field-Flow Fractionation Coupled with ICP-MS for the Analysis of Engineered Nanoparticles in Environmental SamplesThis article provides an overview of the capabilities of field-flow fractionation coupled with inductively coupled plasma–mass spectrometry and demonstrates that the technique shows a great deal of promise to separate, detect and quantitate nanoparticles in environmental matrices.
Latest:
Toward Quantitative Imaging Mass SpectrometryThe main limitations of quantification using MALDI imaging are discussed and the different approaches used for quantitative measurement in MSI are evaluated.
Latest:
Astaxanthin from Shrimp By-products for Active Packaging SystemsThe two year international project "Preparation of active packaging with antioxidant and antimicrobial activity based on astaxanthin and chitosan",1 which started in 2009, was funded by FONCYCIT (Fund for International Cooperation of Science and Technology between the European Union and Mexico).
