Sonja Schneider is manager, Applications Development at Agilent Technologies. She has led the application development team in Waldbronn, Germany, since 2016.
2D-LC –MS Characterization of Charge Variants Using Ion Exchange and Reversed-Phase Chromatography
July 1st 2016This application note demonstrates the analysis of charge variants of Rituximab (both innovator and biosimilar molecules) using multiple heart-cutting two-dimensional liquid chromatography (2D-LC) with mass spectrometry (MS) detection.
ISET – Emulation of Agilent 1100 Series Binary LC
January 11th 2016Agilent Intelligent System Emulation technology (ISET) in the Agilent 1290 Infinity II LC facilitates the transfer of methods from conventional HPLC systems such as the Agilent 1100 Series Binary LC. This Application Note illustrates the advantages of ISET for the analysis of six tricyclic antidepressants.
ISET – Emulation of Agilent 1100 Series Binary LC
January 11th 2016Agilent Intelligent System Emulation technology (ISET) in the Agilent 1290 Infinity II LC facilitates the transfer of methods from conventional HPLC systems such as the Agilent 1100 Series Binary LC. This Application Note illustrates the advantages of ISET for the analysis of six tricyclic antidepressants.
Analysis of Anti-epileptic Drugs
January 11th 2016This Application Note shows the transfer of an analysis method for anti-epileptic drugs from HPLC to UHPLC using the Agilent 1290 Infinity II LC system. An enormous time and solvent saving of approximately 95 % was achieved with an UHPLC separation optimized for speed.
Impurity Testing of Fixed-Dose Combination Drugs
January 11th 2016The Agilent 1290 Infinity II High Dynamic Range Diode Array Detection Impurity Analyzer Solution combines the signals from two diode array detectors with different path length Max-Light cartridge cells to increase the linear dynamic UV-range. This solution can be used to detect and quantify main and trace compounds in a single run without exceeding the linear UV-range.
Analysis of Anti-epileptic Drugs
January 11th 2016This Application Note shows the transfer of an analysis method for anti-epileptic drugs from HPLC to UHPLC using the Agilent 1290 Infinity II LC system. An enormous time and solvent saving of approximately 95 % was achieved with an UHPLC separation optimized for speed.
Ultrafast Analysis of Food Preservatives Using Dual-Needle Injection
January 11th 2016Ultrahigh throughput is shown for ultrafast gradients with over 60 % reduction of total analysis time using alternating column regeneration. This was accomplished with parallel injection by the second needle installed in the Agilent 1290 Infinity II Multisampler, which has a dual-needle option for the analysis of food preservatives.
Ultrafast Analysis of Food Preservatives Using Dual-Needle Injection
January 11th 2016Ultrahigh throughput is shown for ultrafast gradients with over 60 % reduction of total analysis time using alternating column regeneration. This was accomplished with parallel injection by the second needle installed in the Agilent 1290 Infinity II Multisampler, which has a dual-needle option for the analysis of food preservatives.
Impurity Testing of Fixed-Dose Combination Drugs
January 11th 2016The Agilent 1290 Infinity II High Dynamic Range Diode Array Detection Impurity Analyzer Solution combines the signals from two diode array detectors with different path length Max-Light cartridge cells to increase the linear dynamic UV-range. This solution can be used to detect and quantify main and trace compounds in a single run without exceeding the linear UV-range.
Determination of Phenolic Compounds in Virgin Olive Oil Using Comprehensive 2D-LC
March 1st 2015This application note demonstrates how comprehensive 2D-LC can be used to resolve the complex mixture of hydrophilic phenols found in virgin olive oil and investigates differences in the phenol composition of several olive oils.