Biological, Medical, and Clinical Analysis

Until recently, a promising solution to couple capillary electrophoresis to electrospray ionization mass spectrometry has only been available to a small group of experts.

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Poplar buds could hold untapped potential as an ingredient in anti-ageing skin creams, a study has found.

Researchers at Rensselaer Polytechnic Institute in New York, USA, have developed a new technique that allows researchers to collect large amounts of biochemical information from nanoscale bone samples.

Thin Layer Chromatography industrial distribution

The 2011 Manfred Donike award for scientific excellence in sports-doping testing has been presented to Simon Beuck and Nicolas Leuenberger.

Aggregated singletons for automated purification workflow delivers 30 mM DMS solutions for biological screening.

A simultaneous headspace-GC–FID method was validated to establish methanol and ethanol assessment in blood, urine and saliva.

In this review, practical principles and guidelines for designing LC?LC methods are given.

Comprehensive two-dimensional gas chromatography is a powerful technology for separating complex samples and therefore is well suited for non-targeted analysis.

The Singapore Eye Research Institute will advance biomarker candidates that it has identified for chronic inflammatory eye conditions into large-scale clinical trials for validation using AB SCIEX technology.

Effective analysis of branched glycopeptides using porous graphite chromatography

In this review, practical principles and guidelines for designing LCxLC methods are given.

The Canadian National Research Council?s Institute for Marine Biosciences (NRC-IMB) has signed an agreement with AB SCIEX that will enable researchers worldwide to benefit from the insitute?s experience in the detection and identification of marine and freshwater biotoxins and the creation of certified reference materials.

In 1958 the University of Chicago zapped a simulated primordial earth atmosphere with a series of electrical discharges to demonstrate the way in which organic compounds may have been originally synthesized on Earth. Archived and unreported samples have recently been uncovered and submitted to modern analytical techniques, which have revealed even more abundant amino acid and amine yields than previous experiments.

Microextraction by packed sorbent is a sample preparation technique that can be connected on-line with LC or GC systems.

The ability to determine vitamin D levels in patients rapidly and reliably is a valuable tool in identification and management of treatment regimes.

The growing market for biotherapeutic peptides and the development of quantitative methods for those analytes has brought to light the challenges facing the analysis of this broad range of compounds. Market forces and regulatory requirements are encouraging analytical groups to develop methodologies that are time- and cost-effective, while still producing assays that are sensitive enough to cope with biological matrices.

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This article focuses on two of the more common techniques applied to the analysis of a series of benzodiazepines in a biological matrix.

When electrostatic effects are superimposed on hydrophilic interactions, specific functional groups can be targeted.

Agilent Technologies has announced that Merck-Serono has selected the company?s OpenLAB ELN to enhance scientific collaboration globally throughout R&D for finding new small molecules and biopharmaceuticals.