Biological, Medical, and Clinical Analysis

The advantages of HPLC-Chip-MS workflow over conventional methods of N-glycan analysis

A study into the composition of krill oil may offer new insights into the complexity of this source of omega-3.

Following the accident at Chernobyl Nuclear Power Plant in 1986, the surrounding area remains substantially contaminated with radioactive isotopes. A study into the adaptations of the surrounding plant life has suggested that the plant proteomes remain largely unchanged by the radio contamination.

A simple and rapid HPLC method was established to simultaneously determine the active ingredients of red clover.

Scientists at the Swiss Federal Institute of Technology, in collaboration with the Institute for Systems Biology in Seattle, Washington, USA, have created assays for approximately 20?000 human proteins, generating what is claimed to be the world?s first human Multiple Reaction Monitoring Atlas.

Accurate and sensitive all-ions quantification using ultra-high resolution LC-MS

Using SRM and H-SRM on an Integrated UHPLC-MS Platform for Sensitive, Accurate and Reproducible Quantification of Perfluorinated Compounds in Human Breast Milk.

Spark Holland Application Note

Waters Application Note

Agilent Technologies Application Note

Dionex Application Note

Thermo Fisher Scientific Application Note

Wyatt Technology Application Note

Thermo Fisher Scientific Application Note

Agilent Technologies has announced that a group of researchers from the University of California, Davis, USA, has found that human breast milk contains an unexpected abundance of sugars that coats the lining of infants? intestines, protecting it from noxious bacteria.

A simple rapid HPLC method for simultaneously determiing formononetin, biochanin A, daidzen and genistein in Red Clover

Characterizing PEGylated Proteins by MALS-UV-RI Detection

A study published in PLoS ONE has provided the most comprehensive protein profile of cerebrospinal fluid to date, using liquid chromatography to identify 2630 proteins, nearly three times the number previously identified.

LGC is to extend its hair drug analysis services in Europe, following an agreement to market a hair test from drug testing company, Psychemedics.

Characterizing biologics through chromatographic analysis.

The analysis of clozapine and norclozapine in plasma using automated on-line sample preparation and LC–MS/MS

Global health and safety concerns now play a key role in driving innovation of liquid chromatography systems and the uptake of advanced LC technology, such as UHPLC.

An HS-GC-FID method for the determination of ethanol and methanol content in biological fluids is presented.

Peas, beans and some other plant seeds contain proteins, called globulins, which have been shown to act as a defence against insects and other herbivores. Coffee beans contain large amounts of globulins, so scientists in Brazil studied the beans to assess their potential for warding off insects.

Two-dimensional polyacrylamide gel electrophoresis reveals regulatory effects of dietary polyunsaturated fatty acid supply on protein expression in early development.

This article features some of the most frequently used HPLC applications for the characterization of biopharmaceuticals.

How the combination of an electroextraction with hollow-fibre liquid-phase microextraction can lead to a selective, rapid method

Explaining the importance of sensitive detection in phthalate testing during GC–MS analysis.

How the combination of an electroextraction with hollow-fiber liquid-phase microextraction can lead to a selective, rapid new method.

Driving under the influence is a serious criminal offense. To prove a suspect guilty calls for solid scientific evidence. The generally accepted method is to accurately measure the blood alcohol content. This article presents a static headspace-gas chromatography method, which offers reliable qualitative analysis, reproducibility, and short run times to allow for high throughput.