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Researchers from Colorado State University have demonstrated the viability of exploratory metabolomics and HILIC–MS in identifying biomarkers associated with dengue virus (DENV) infections, such as dengue fever, dengue haemorrhagic fever/dengue shock syndrome (DHF/DSS).

A team of researchers from the State Laboratory of Chemo/Biosensing and Chemometrics in China has developed a novel high performance liquid chromatography-diode array detection (HPLC–DAD) method for the identification of six synthetic colours in five beverages.

In this Q&A, we will talk to Dr. Arthur Fitchett, Director of Sales Training at Thermo Fisher Scientific. We will discuss recent advances in ion chromatography technology, what they mean for different types of IC analyses, and how they can improve results in your laboratory.

Click the title above to open The Column May 06, 2016 Europe & Asia issue, Volume 12, Number 8, in an interactive PDF format.

Click the title above to open The Column May 06, 2016 North American issue, Volume 12, Number 8, in an interactive PDF format.

Using supercritical CO2

LCGC magazine is pleased to announce the addition of Deirdre Cabooter to the editorial advisory boards of LCGC North America and LCGC Europe.

This new e-book considers what functions and features should be available in an ideal chromatography data system (CDS) for use in a regulated analytical laboratory.

Click the title above to open the LCGC Europe May 2016 Recent Developments in LC Column Technology Supplement, Vol 29, No s5, in an interactive PDF format.

Whole blood analysis is an emerging trend in the field of bioanalysis. We developed a fast and simple protocol to extract and analyze a peptide, hepcidin, from whole blood. Sampling and extraction were carried out using volumetric absorptive microsampling (VAMS), a novel blood collection device that allows the sampling of a known blood volume independently from hematocrit. The composition of the extraction medium was optimized using an experimental design to get the most intense signal of hepcidin, considering different organic solvents and acidic additives.

A commentary on maintaining and growing technical competencies and the effort that is required.

The SFC conference tackled theory, economics, scale-up, and more.

A look at the inspirations and future plans of a leading young scientist.

Detecting impurities in any chemical reaction is becoming increasingly important to detect those present at low levels (for example, 0.5%).

Click the title above to open the LCGC Europe May 2016 regular issue, Vol 29, No 5, in an interactive PDF format.

Click the title above to open the LCGC North America May 2016 regular issue, Vol 34 No 5, in an interactive PDF format.

Click the title above to open the May 2016 issue of Current Trends in Mass Spectrometry, Volume 14, Number 2, in an interactive PDF format.

Ted Szczerba, Technical Director of Chromatography and SFC Separations at Regis Technologies, overviews incorporating Supercritical Fluid Chromatography (SFC) into his separations lab. With over 30 years experience working with chiral compounds and over 10 years running SFC, he assesses the value of the technique versus the drawbacks of what is available in the field today. Learn about a typical screening day and this industry veteran's advice on what is needed for an effective separations process.

Your current contract laboratory and instrument provider may be familiar and comfortable, but, maintaining the status quo doesn’t lead to greater rewards. In fact, it often involves putting up with less-than-desired results. Join us in this executive summary to hear how Ajinomoto Althea develops unsurpassed solutions for biopharma companies, and how a team at Thermo Fisher Scientific has challenged the status quo to deliver uncompromised UHPLC.

LCGC magazine is pleased to announce the addition of Debby Mangelings to the editorial advisory boards of LCGC North America and LCGC Europe.

Subcritical water chromatography (SBWC) is seen as an increasingly enticing prospect to replace high performance liquid chromatography (HPLC) in industrial settings because of its low costs and environmental impact. Yu Yang of East Carolina University, in Greenville, North Carolina, USA, has conducted research into this process for two decades. He recently spoke to Lewis Botcherby of The Column about his work, why companies should consider SBWC, and its role in pharmaceutical analysis.

Trajan Scientific and Medical (Melbourne, Australia) has announced the acquisition of LEAP Technologies Inc. (Carrboro, North Carolina, USA).

An Advanced Grant worth 2.5 million Euros has been awarded to Peter Schoenmakers of the University of Amsterdam (UvA) to develop new high-performance separation technology.

This year, LCGC is pleased to honour Debby Mangelings as the winner of the 2016 Emerging Leader in Chromatography Award. Mangelings received her award on Monday 7 March during an oral symposium at Pittcon 2016 in Atlanta, Georgia, USA.

Researchers from Heilongjiang University of Chinese Medicine, China, have used ultrahigh-performance liquid chromatography coupled to mass spectrometry and metabolomics to investigate the metabolic networks of Alzheimer’s disease, identifying potential biomarkers and biochemical mechanisms.

The literature on reversed-phase liquid chromatography (LC) of proteins is reasonably well developed, but not taught in the college classroom much. Kevin Schug therefore wants to focus on a stoichiometric displacement model for reversed-phase LC of proteins and why it is particularly insightful from a practical perspective.

This is the first of a four-part series of articles exploring current topics in separation science that will be addressed at the HPLC 2016 conference in San Francisco, USA, from 19–24 June.

The 40th International Symposium in Capillary Chromatography (ISCC) and 13th GC×GC Symposium will be held at the Palazzo dei Congressi, in Riva del Garda, Italy, from 29 May–3 June 2016.