Georges Guiochon Faculty Fellowship Award
June 20th 2016The Georges Guiochon Faculty Fellowship award will be presented at 7:00 pm on Monday, June 20. This year’s awardee is Dr. Ying Ge, who is an associate professor in the Department of Cell & Regenerative Biology and the Department of Chemistry at the University of Wisconsin-Madison.
2016 Uwe D. Neue Award in Separation Science
June 20th 2016The 2016 Uwe D. Neue Award in Separation Science will be presented at 7:00 pm on Monday, June 20, after the Georges Guiochon Faculty Fellowship Award. This year’s awardee is Lloyd Snyder, who is retired from LC Resources. Synder is known not only for his many important contributions to an understanding of high performance liquid chromatography (HPLC), but also for his teaching, mentoring, and acclaimed publications.
Today’s Tutorials: Sample Prep, UHPLC, High-Pressures, and Why Small-Molecules Matter in Biopharma
June 20th 2016Today’s free tutorial sessions at the HPLC 2016 conference will cover a range of topics, from trends in sample preparation and the use of high pressures, to fundamentals of ultrahigh pressure liquid chromatography (UHPLC), to the role of small-molecule analysis in biopharma.
Bell, Regnier, Sweedler, and Haddad Give Free Tutorials Today
June 20th 2016Today at the HPLC 2016 conference, four free tutorial sessions are offered to HPLC conferees. Today’s talks, from Dave Bell, Fred Regnier, Jonathan Sweedler, and Paul Haddad, cover hydrophobic interaction chromatography (HILIC), protein analysis, manuscript preparation, and HPLC method development.
Evaluating the Potential of HPLC with IMS-MS for Metabolomics
June 20th 2016Multidimensional liquid chromatography strategies are the most widely used method for increasing the number of spatially resolved components and reducing stress on mass spectrometric detection. However, the stress placed on a secondary dimension in a comprehensive on-line methodology is very high. An increasingly attractive approach is the coupling of high performance liquid chromatography (HPLC) with ion mobility spectrometry hyphenated to mass spectrometry (IMS-MS). Tim Causon and Stephan Hann of the University of Natural Resources and Life Sciences in Vienna, Austria, spoke to The Column about their work evaluating this approach and exploring its possibilities for metabolomics.
ChromSoc’s Lake District Lectures for Students
June 20th 2016The Chromatography Society is holding a four-day educational event in the Lake District from 14–17 October at the Wordsworth Hotel in Grasmere. Aimed at post-graduate students and novice chromatographers, the event will focus on the fundamentals of liquid chromatography and its practical application in industry and academia.
Dwight Stoll Receives Two New Awards
June 10th 2016Dwight Stoll, an associate professor of chemistry at Gustavus Adolphus College in Saint Peter, Minnesota, was honored recently with two awards: the 2016 Gustavus Faculty Scholarly Achievement Award, presented at the college’s annual Honor’s Day Convocation in May, and the 2016 Palmer Award, presented at the Minnesota Chromatography Forum (MCF) Spring Symposium, also in May.
Generic UHPLC Method for the Simultaneous Analysis of Compounds with a Wide Range of Polarities
June 7th 2016Appropriate analytical methods are required to evaluate the presence, metabolism, degradation, and removal of specific compounds in complex mixtures. There is an increasing demand to analyze samples with a wide range of polarities in a variety of applications, including environmental analysis, biomarker discovery, and proteomics. Multiple analyses on complementary columns are often needed to cover the separation of all compounds with a large difference in polarity. This article describes a generic method involving an ultrahigh‑pressure liquid chromatography (UHPLC) system equipped with two external switching valves to connect hydrophilic interaction liquid chromatography (HILIC) and reversed-phase LC columns in series for the sequential analysis of polar and apolar compounds.
Nontargeted Metabolite Profiling in Next-Generation Plant Breeding: A Case Study in Malting Barley
June 7th 2016Nontargeted metabolite profiling by ultrahigh-pressure liquid chromatography–mass spectrometry (UHPLC–MS) is a powerful technique to investigate the influence of genetic and environmental factors on metabolic phenotypes in plants. The approach offers an unbiased and in-depth analysis that can reveal molecular markers of desirable phenotypic traits that can be complementary to genetic markers in plant breeding efforts. Here, the power of nontargeted metabolite profiling is illustrated in a study focused on the determination of molecular markers in malting barley that are predictive of desirable malting quality for brewing applications.
The LCGC Blog: Investigating (and Solving) Robustness Issues in HPLC
June 7th 2016Not every method is as we would hope it would be. Some methods come to us in imperfect form and we have to live with them, while others are difficult separations and, by necessity, need to be developed using close control of several variables such as eluent pH, eluotropic strength, ionic strength etc.