Thermo Fisher Partner with University of Birmingham’s New Phenome Centre
June 6th 2016Thermo Fisher Scientific has extended a technology collaboration with the University of Birmingham in the UK. Thermo Fisher will supply a range of mass spectrometry instruments to be used at the University’s new Phenome Centre.
Waters Announces Additions to Leadership Team
June 6th 2016Waters Corporation has announced the addition of Richard Chang and Xiao Ran Yu to its Asia Pacific leadership team. Chang has been appointed as Vice President of Waters’ Asia Pacific Operations and Yu has been appointed as General Manager of Waters China.
Overcoming Fear, Uncertainty, and Doubt in GPC: The Need for an Absolute Measurement of Molar Mass
June 2nd 2016While conventional calibration for gel permeation (GPC) or size-exclusion chromatography (SEC) is useful, there are inherent disadvantages in this type of analysis that introduce experimental error. This uncertainty may cast serious aspersions on the rigour and utility of the results. Multi-angle light scattering (MALS) detection is quite simple to add to an existing chromatography system and can help overcome the challenges faced with single detector chromatography and conventional calibration-based methods. An alternative separation technique called asymmetric flow field-flow fractionation (AF4) offers tunable, column-free fractionation.
Separation Science in Drug Development, Part 3: Analytical Development
June 1st 2016The third instalment in this series provides an overview of modern practices of separation science in small-molecule drug development. It highlights approaches in high performance liquid chromatography (HPLC) method development and physical or chemical characterization to support process chemistry and formulation development, and for assessment or control of clinical trial materials. The roles of separation scientists in analytical development and salient chromatographic methodology trends are also discussed.