November 12th 2024
The method of standard additions (MoSA) enables quantification of volatile impurities in condensed-phase samples, such as emulsions, for which matrix-matched calibration standards are required. The technique is, however, expensive because it requires multiple analyses of each sample.
Ion Chromatography Method for Determination of Risedronate in Pharmaceutical Preparations
September 1st 2011Risedronate, a pyridinyl bisphosphonate, is one of the most popular first-line drugs in the treatment of osteoporosis, Paget's disease, and other bone fragility conditions. In October 2010, the United States FDA approved a second-generation risedronate in a delayed-release formulation.
Determining Carbohydrates in Essential and Non-essential Foodstuffs using Ion Chromatography
December 2nd 2010This article describes a straightforward ion chromatographic method that uses isocratic elution and pulsed amperometric detection (PAD) to sensitively determine water-soluble polyols and sugar alcohols as well as mono-, di- and oligosaccharides in essential and non-essential foodstuffs. While carbohydrate determination of most foodstuffs requires only minimal sample preparation such as dilution and filtration, samples with interfering matrices such as protein-containing dairy products have to be dialysed before injection.
Determining Carbohydrates in Essential and Nonessential Foodstuffs Using Ion Chromatography
December 1st 2010This article describes a straightforward ion chromatographic method that uses isocratic elution and pulsed amperometric detection (PAD) to sensitively determine water-soluble polyols and sugar alcohols as well as mono-, di- and oligosaccharides in essential and nonessential foodstuffs.
Sulphur and Halide Determination by Combustion Ion Chromatography
July 2nd 2010The fully automated combustion ion chromatography (CIC) system presented here combines a highly efficient combustion system with the separation power of ion chromatography (IC). CIC allows for the simultaneous, speciated trace analysis of halide (F, Cl, Br and I) and sulphur compounds (as sulphate) from sub-ppm to percent levels in any nonaqueous sample matrix.