Ion chromatography (IC) is an important analysis tool for chromatographers. Typically, emphasis is placed on the hardware components and chemistry to achieve the ideal level of separation. However, the flow path itself is often overlooked, and there are some relatively simple steps that can be taken to ensure that the system's flow path positively affects the overall chromatographic results achieved.
Ion chromatography (IC) is an important analysis tool for chromatographers. Typically, emphasis is placed on the hardware components andchemistry to achieve the ideal level of separation. However, the flow path itself is often overlooked, and there are some relatively simple stepsthat can be taken to ensure that the system’s flow path positively affects the overall chromatographic results achieved.
Overcoming Common Challenges to Determine Residual Impurities Using IC in APIs with Limited Water
December 10th 2024Organic solvents are generally not compatible with ion chromatography (IC) systems. The approach presented here assists the use of organic solvents for sample preparation and provides a mechanism for the removal of the organic solvents from the chromatographic flow path.