This review aims to provide a summary of the most current analytical techniques and their applications in per- and polyfluoroalkyl substances (PFAS) research, contributing to the ongoing efforts to monitor and mitigate PFAS contamination.

Microscopic illustration of DNA double helix structure, highlighting gene silencing techniques with RNA interference, CRISPR-Cas9, and antisense oligonucleotides, for genetic research applications. | Image Credit: © john - stock.adobe.com

Systematic Evaluation of HILIC Stationary Phases for MS Characterization of Oligonucleotides

By Jordy J. Hsiao
Lee J. Bertram

Alex Apffel
Andrea Angelo P. Tripodi
Andrew Coffey
Ta-Chen Wei
Connor Flannery

October 15th 2024

Hydrophilic interaction chromatography–mass spectrometry (HILIC-MS) offers a flexible and efficient alternative to ion-pairing reversed-phase liquid chromatography (IP-RPLC) for oligonucleotide analysis, with column selectivity and mobile phase pH being key factors in optimizing retention and detection.

Complete air sampling device with pump, stand, thoracic selector head and fan, designed to count airborne asbestos fibres | Image Credit: © Pvince73 - stock.adobe.com

New Algorithm Created for Detecting Volatile Organic Compounds in Air

By Aaron Acevedo

October 9th 2024

Scientists from Institut de Combustion, Aérothermique, Réactivité et Environnement (ICARE-CNRS) in Orléans, France and Chromatotec in Saint-Antoine, France recently created a new algorithm for detecting volatile organic compounds (VOCs) in ambient air.

Best of the Week: Machine Learning in Measurements, AOAC International Awards

By Aaron Acevedo

October 4th 2024

Here is some of the most popular content posted on LCGC International this week.

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