All News

As the need for improvements in the yield, insect resistance, and abiotic stress tolerance of crop plants continues to increase, Gia C. Fazio and colleagues Wayne Skinner, Zina Dahmani, Yingzhi Lu, and Jean C. Kridl have collaborated on a paper that describes the use of liquid chromatography–mass spectrometry (LC–MS) to quantify the expression of levels of a transgenic protein, barley alanine aminotransferase, across multiple rice lines.

Shimadzu has announced that, in partnership with the Sugiyama Laboratory within the RIKEN Innovation Centre of the RIKEN Research Cluster for Innovation, it has started research on quantitative analysis methods using LC–MS–MS to support drug discovery using microdosing.

PerkinElmer, Inc., (Waltham, Massachusetts, USA) has announced that it is to establish a personalized health innovation centre of excellence.

Click here to view the complete E-Separation Solutions newsletter from July 5, 2012.

Surfactant Analysis

Agilent Technologies (Santa Clara, California, USA) has announced the recipients of its latest Thought Leader award: Dr Jens Frisvad and the centre for microbial biotechnology in the department of systems biology at the Technical University of Denmark.

A team of researchers from Australia has conducted a study into the way in which Drakaea livida (Orchidaceae) is pollinated.

A team of scientists from Taiwan has developed a nanoparticle/virus mass spectrometry technique to make rapid and accurate mass and mass distribution measurements of nanoparticles and viruses.

Waters (Milford, Massachusetts, USA) and the Food and Environment Research Agency (Fera) (York, UK) have announced that they will open a new laboratory-based training facility which will combine their respective regulatory, scientific and industry expertise to help solve the global food safety challenge.

Agilent Application Note

Phenomenex Application Note

Phenomenex Application Note

A Toolkit for GC Troubelshooting

The new version of EU GMP Annex 11 has been effective for about a year. There are new technical requirements in the Annex – do your laboratory computerized systems comply with them all? In this column we look at the impact of these new regulatory requirements for Good Manufacturing Practice laboratories.

Nitrile rubber materials were studied using flash analytical pyrolysis-GC–MS to demonstrate that this technique is a good tool to identify the additives in nitrile rubber.

A brief historical overview of DMS, followed by a synopsis of the instrumentation, physics, and chemistry behind the separation principles

Detailed study results challenge common beliefs about the mechanisms behind the excellent performance of core–shell particles.

In both East and West, new ideas have often met resistance.

DIP–MS is a fast and easy tool that can identify classes of compounds in opportunity crudes (heavy and ultraheavy crude oils, asphaltenes, and tar sands) in the field, without prior separation or treatment. It may enable fast screening of real samples to make a rough evaluation of the potential of reservoirs and oil fields.

A discovery-based, untargeted metabolomics analysis of hundreds of yeast metabolites under robust, controlled extraction conditions followed by identification is described.

The main limitations of quantification using MALDI imaging are discussed and the different approaches used for quantitative measurement in MSI are evaluated.

Many tools gas chromatographers keep on hand are specialized, but others can be found in the toolkits of plumbers and carpenters.

In a well-behaved method, changes in peak shape should occur gradually over hundreds or thousands of samples. Tailing of one or a few peaks usually points to a problem.

Crop development to improve yield or disease resistance has been explored for centuries and the technologies to measure these improvements have subsequently become complex.

Event news summary

Gradients can provide improved peak shape, higher efficiency, and sometimes altered selectivity and improved resolution.

Click the title above to open the LCGC North America July 2012 regular issue, Vol 30 No 7, in an interactive PDF format.

Click the title above to open the July 2012 issue of Current Trends in Mass Spectrometry, Volume 10, Number 3, in an interactive PDF format.

Chiral separations are important in several application areas, most notably in pharmaceutical analysis. Participants in this Chiral Technology Forum include Chris Hamman and Mengling Wong of Genentech, Marc Jacob of Phenomenex, and Zachary S. Breitbach of the University of Texas at Arlington, Arlington, Texas, USA.