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Analytical method validation is the process of demonstrating that a method does what it is intended to do.

The stationary phases currently in use for modern thin-layer chromatography (TLC) are reviewed.

Wyatt Technology Application Note

Polymer Standards Service GmbH Application Note

KineMed Inc., (Emeryville, California, USA) and CHDI Foundation (New York, USA) have announced a collaboration that will see KineMed?s isotopic labelling and dynamic proteomics platform be used to investigate the turnover rates of huntingtin protein.

Innovative technologies are rapidly helping to measure the numerous and diverse lipids present in biological samples. In this second and final instalment of the series, the authors present and discuss the use of these technologies for lipid analysis.

Event news summary

Will an internal standard always improve data quality?

This month's "Sample Prepartion Perspectives" describes practical aspects of hollow-fibre liquid-phase microextraction in the three phase mode (HF3LPME) and also electromembrane extraction (EME), which uses an electrical potential as the driving force for the extraction.

Click the title above to open the LCGC Asia Pacific June 2012 regular issue, Vol 15, No 2, in an interactive PDF format.

Click the title above to open the LCGC North America June 2012 Application Notebook, Vol 30 No s6, in an interactive PDF format.

Click the title above to open the LCGC North America June 2012 regular issue, Vol 30 No 6, in an interactive PDF format.

Fasha Mahjoor, founder and CEO of Phenomenex (Torrance, California) was appointed as one of one of Outward Bound Trust's (Cumbria, UK) "25 Strong Chairman's Group" members.

Bioanalysts are faced with a variety of separations challenges, including how to select appropriate stationary phases and problems with sample preparation and clean-up. Participants in this technology forum are Maureen Joseph and Linda L. Lloyd of Agilent Technologies; Patrik Appelblad, Ling Bei, and Dave Lentz of EMD Millipore; and Jason P. Weisenseel of PerkinElmer.

Bioanalysts are faced with a variety of separations challenges, including how to select appropriate stationary phases and problems with sample preparation and clean-up. Participants in this technology forum are Maureen Joseph and Linda L. Lloyd of Agilent Technologies; Patrik Appelblad, Ling Bei, and Dave Lentz of EMD Millipore; and Jason P. Weisenseel of PerkinElmer.

The Centre for Genomic Regulation (CRG) (Barcelona, Spain) and the Fundació ACE - Barcelona Alzheimer Treatment & Research Centre (Barcelona, Spain) have signed an agreement to collaborate on scientific projects related to neurodegenerative diseases.

Empire Genomics (Buffalo, New York, USA) has announced that it has chosen Funakoshi as a distributor of its product portfolio for the Japanese market.

Agilent Technologies Inc. (Santa Clara, California, USA) has announced that it is to acquire Dako (Glostrup, Denmark), the cancer diagnostic company.

Complete Genomics Inc. (Mountain View, California, USA) has announced that it has signed four distributor agreements with Asia-Pacific life sciences companies ? GeneWorks Pty Ltd. in Australia, Cyagen Biosciences in China, AR Brown Co. Ltd. in Japan and BML in Korea.

Kromasil HILIC-D is designed for the best selectivity of polar compounds.

Waters EU - Maximizing HPLC Productivity with 2.5 µm Extended Performance (XP) Columns

Agilent Technologies Inc. (Santa Clara, California, USA) has announced that it is to acquire Dako (Glostrup, Denmark), the cancer diagnostic company.

Agilent (Santa Clara, California, USA) has announced the winner of the fourth annual Agilent Early Career Professor Award.

Monday afternoon?s six presentations will provide insight into a variety of ambient ionization applications along with the methods and instruments used in this technique, including gas chromatography-ambient mass spectrometry, surface acoustic wave nebulization, spatially resolved laser induced forward transfer of material followed by liquid microjunction surface sampling, probe electrospray ionization, and laser ablation electrospray ionization mass spectrometry.

This session includes presentations of quantitative studies performed using mass spectrometry techniques ranging from ultratrace analysis of small molecules in complex samples, to bioanalysis of microsamples, to LC?MS-MS analysis at low flow rates, and MS applications in clinical toxicology.

The Broad Institute (Cambridge, Massachusetts, USA) and Fluidigm Corporation (South San Francisco, California, USA) have announced the launch of a research centre dedicated to accelerating the development of research methods and discoveries in mammalian single-cell genomics.

Catherine C. Fenselau, professor of chemistry and biochemistry at the University of Maryland, is the 2012 recipient of the Award for a Distinguished Contribution in Mass Spectrometry, granted by the American Society for Mass Spectrometry (ASMS). The award honors her pioneering work to apply mass spectrometry to the rapid identification and characterization of intact microorganisms.

This session includes presentations on biotherapeutics and their impurities, including protein pharmaceuticals, glycans, glycopeptides, antibody-drug conjugates and more.

The impact of the oil spill in the Gulf of Mexico is still creating headlines two years later. Helen White, assistant professor of chemistry at Haverford College, Haverford, Pennsylvania, USA, has published a paper on her group's findings from the spill. LCGC's E-Separation solutions spoke to her to find out more.

Wyatt Technology?s Möbius is the first and only light scattering instrument that makes reliable, reproducible, and non-destructive zeta potential measurements of macromolecules as small as 1 nm, under dilute solution conditions.