All
Determination of Fatty Acid Methyl Esters (FAMEs) in Salmon Oil Using Automated Sample Preparation
May 1st 2012The automated derivatization of fatty acids (FAs) was performed with the Agilent 7696A Sample Prep WorkBench. Since free fatty acids show tailing in gas chromatography, transformation of fatty acids into fatty acid methyl esters (FAMEs) is widely used.
Ultratrace Quantitative Analysis of Catalyst Poisoners using a Dedicated GC–MS Analyser
April 1st 2012A GC–MS analyser is described that is reported to substantially expand the workable application range of a classic catalyst contaminants analyser. The use of FS/SIM mode permits identification of unknown contaminants in combination with reliable quantification at trace and ultratrace amounts.
The Potential of Polymer Monolithic Capillary Columns for the LC–MS Analysis of Intact Proteins
Describes the preparation of a reversed-phase monolithic column with an optimized porous structure to separate intact proteins using LC–MS.
Liposome Characterizatio by FFF–MALS–QELS
February 1st 2012Liposomes are made of lipid bilayers and are often used in drug delivery by encapsulating the core with therapeutic drugs. During liposome research, formulation, manufacturing, and quality control, it is of great importance to monitor liposome size and encapsulation.
Faster, More Sensitive Determination of Carbamates in Drinking Water
February 1st 2012U.S. EPA Method 531.2 describes the determination of widely used carbamate pesticides in raw surface water using HPLC with fluorescence detection following postcolumn derivatization, which enhances method sensitivity and selectivity as compared to UV absorbance detection.
Analysis of Over 15 Million Dalton Polymers by Aqueous SEC Method
February 1st 2012Size exclusion chromatography (SEC) is a simple HPLC technique used for the molecular weight (MW) distribution analysis of polymers. Several manufacturers provide SEC columns with different base materials and various pore sizes to cover a wide range of polymer analysis.
LC–MS-MS Method for the Determination of Enalapril and Enalaprilat fro Human Plasma Using SOLA
February 1st 2012A liquid chromatography tandem mass spectrometry method for enalapril and enalaprilat from human plasma has been developed using Thermo Scientific SOLA cartridges. Sample preparation is fast, efficient, and reproducible giving excellent recovery levels for each compound.
Microwave Assisted Extraction of Dioxins and Furans Compared to Soxhlet
February 1st 2012Microwave assisted extraction (MAE) offers significant benefits over traditional soxhlet extraction for dioxins and furans determination from environmental samples including higher sample throughput, time savings, reduced solvent and great reproducibility.
Fast Cap IC Determinations of Inorganic Anions and Cations in Drinking Water
February 1st 2012The determination of common inorganic anions and cations in drinking water is important due to the toxicity of anions (e.g., fluoride, nitrite, and nitrate) and secondary contaminants (e.g., chloride and sulfate) which can affect the water's aesthetics.
Screening for Pyrethroid Insecticides in Sediment Samples by GC–MS-MS
February 1st 2012A simple screening method for Pyrethroid insecticides in sediment samples is described. Electron impact ionization (EI) with tandem MS-MS in combination with programmed temperature vaporization injection (PTV) were used in order to obtain excellent specificity and low limits of detection.
Quantitation of Omega Fatty Acids by HPLC and Charged Aerosol Detection
February 1st 2012Omega-3 and -6 fatty acids are essential compounds required for normal growth. Omega-3 consumption is purported to have a number of health benefits, e.g., cancer prevention, cardiovascular disease prevention, and improved immune function. Although both omega-3 and -6 fatty acids can give rise to eicosanoid-signaling molecules (prostaglandins, prostacyclins, thromboxanes, and leukotrienes), the omega-6 eicosanoids are generally proinflammatory. A person's diet requires a balance of omega fatty acids at suitable levels.
Analysis of Multiple Classes of Cigarette Smoke Constituents by GCxGC-TOFMS
February 1st 2012GCxGC-TOFMS provided a comprehensive analysis of tobacco smoke. Individual smoke constituents across several target compound classes were extracted, chromatographically resolved, then identified and quantified with mass spectral detection.