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Analysis of Active Cannabis Compounds in Edible Food Products: Gummy Bears and Brownies
June 1st 2019Potency testing in marijuana-infused edibles is a problematic task due to the complexity of the matrices. The concentration of active ingredients in edibles can range from a few ppm to 3.5% (1). In this application, active cannabinoid compounds were extracted from gummy bears (and also brownies, results not shown), followed by HPLC analysis.
An Amino Acid Analysis According to European Pharmacopoeia 8.0
June 1st 2019The European Pharmacopoeia (Ph. Eur.) defi nes requirements for the qualitative and quantitative composition of medicines, as well as the tests to be carried out on medicines and on substances and materials used in their production.
Arsenic Speciation Using Hamilton PRP-X100
June 1st 2019Organic arsenic compounds added to feed stocks of chicken and poultry pose serious environmental and ecological threats. National and worldwide health organizations, such as the U.S. Environmental Protection Agency and the U.S. Food and Drug Administration, have recently implemented more stringent concentration limits for arsenic species in drinking water and foodstuffs.
The Shodex Rapid SUGAR Series: Fast Fermentation Monitoring and Sourdough Cultures
June 1st 2019Living organisms (yeast and bacteria) were not identified as the agents that produced or spoiled common food items until the 19th century. Baking, especially of bread, was among the first industries to be transformed by the emerging scientific understanding of fermentation. The introduction of commercialized yeast in the early 20th century steadily reduced the time needed to bake bread both at home and on the production line, making way for modern packaged breads.
Kinase Fragments Dimerize Without Oligomerization Domains, by SEC-MALS
June 1st 2019Determination of oligomeric states is an important issue in protein chemistry. For example, self-assembly via oligomerization domains is crucial for the regulation of several protein kinases. Determination of the oligomeric state of fragments of these kinases is a means of verifying the involvement of each domain in self-assembly.
Automated SPE to Improve the Recovery of Semivolatile Compounds in Compliance with EPA Method 8270
February 1st 2019This applicate note presents the use of an automated solid-phase extraction (SPE) system to improve the accuracy and precision of semivolatile extractions, in compliance with EPA Method 8270.
Separation of Five Steroids on a Hamilton PRP-C18 Reversed-Phase HPLC Column
February 1st 2019In this study, a reversed-phase HPLC method was developed for separation of five steroid hormones with partition coefficients ranging from 1.47 (cortisone) to 4.5 (pregnenolone) on a Hamilton PRP-C18 HPLC column.
Characterization of TSKgel FcR-IIIA-NPR HPLC Column by Top Down Mass Spectrometry
February 1st 2019The purpose of this study is to demonstrate the use of mass spectrometry to characterize the elution profile of a typical IgG1 molecule separation on a TSKgel FcR-IIIA-NPR column, and verify the observations that certain glycan structures impart higher activity to the monoclonal antibody, especially as it relates to the presence of terminal galactose sugars.