Application Notes

This method showed excellent precision and accuracy for the 12 FDA regulated mycotoxins that were evaluated during a validation study that covered a variety of matrices.

Organic arsenic compounds added to feed stocks of chicken and poultry pose serious environmental and ecological threats. National and worldwide health organizations, such as the U.S. Environmental Protection Agency and the U.S. Food and Drug Administration, have recently implemented more stringent concentration limits for arsenic species in drinking water and foodstuffs.

Living organisms (yeast and bacteria) were not identified as the agents that produced or spoiled common food items until the 19th century. Baking, especially of bread, was among the first industries to be transformed by the emerging scientific understanding of fermentation. The introduction of commercialized yeast in the early 20th century steadily reduced the time needed to bake bread both at home and on the production line, making way for modern packaged breads.

Determination of oligomeric states is an important issue in protein chemistry. For example, self-assembly via oligomerization domains is crucial for the regulation of several protein kinases. Determination of the oligomeric state of fragments of these kinases is a means of verifying the involvement of each domain in self-assembly.

• CESI-MS is vital for nitrosamines analysis in post-harvest fumigation • Results of USDA testing of CESI-MS tools

Solvent-reduced determination of 100 contaminants from low double-digit to low triple-digit pg/L in 100 mL surface water samples, meeting the requirements of the EU-WFD based on SBSE-TD-GC-MS/MS

The Guide to LC Troubleshooting is a valuable resource, not just for analytical chemists but for anyone who uses liquid chromatography. This eBook-containing charts that are published in a logical and easy-to-understand format-discusses common LC problems and their causes, and offers solutions for addressing them in the laboratory.

• Overview of extraction technology in food safety studies • How a single, automated method extracts pesticides from various matrices • Q&A: Improving sample prep for LC/GC analysis of plastics, foods & more

Eliminating laborious sample preparation, field-flow fractionation greatly facilitates the absolute characterization of lignosulfonates by multi-angle light scattering.

• Background on capillary electrophoresis • Importance of glycan screening • Benefits of high-throughput screening with intuitive data analysis

This applicate note presents the use of an automated solid-phase extraction (SPE) system to improve the accuracy and precision of semivolatile extractions, in compliance with EPA Method 8270.

One of the fundamental tenets of chromatography is the interaction between an analyte and stationary phase.

In this study, a reversed-phase HPLC method was developed for separation of five steroid hormones with partition coefficients ranging from 1.47 (cortisone) to 4.5 (pregnenolone) on a Hamilton PRP-C18 HPLC column.

This method showed excellent precision and accuracy for the 12 FDA regulated mycotoxins that were evaluated during a validation study that covered a variety of matrices.

Pickering Laboratories developed an analytical method to comply with all the chromatographic requirements of Commission Regulation (EC) No 152-2009.

For your highly sensitive UHPLC–MS analyses, how can you reduce noise and additional signals to a minimum?

Chitosans are analyzed by SEC-MALS to determine molar mass moments and distributions.

This application note presents calibration plots, RSDs, and MDLs for IEC Method 62321-8 using a CDS Model 6150.

The purpose of this study is to demonstrate the use of mass spectrometry to characterize the elution profile of a typical IgG1 molecule separation on a TSKgel FcR-IIIA-NPR column, and verify the observations that certain glycan structures impart higher activity to the monoclonal antibody, especially as it relates to the presence of terminal galactose sugars.

This application note effectively outlines a simple three-step method for the extraction of loperamide and its main metabolite, N-desmethyl loperamide, from blood.

Here we applied our newly developed UHPLC C18 and C30 columns to oligonucleotide analysis.

In this application, a simple method to simultaneously analyze various water-soluble vitamins was developed.

Sensitive detection of more than 250 pesticide residues in foods using the Agilent Ultivo Triple Quadrupole LC/MS system

Sensitive detection of more than 250 pesticide residues in foods using the Agilent Ultivo Triple Quadrupole LC/MS system

Plastics play a role in just about every market sector and research area including agriculture, food, packaging, pharmaceuticals, medical implants, and personal care products, making the potential leaching of additives like antioxidants or slip additives a major concern. In this article learn how the EDGE is able to extract additives from plastics in a fraction of the time of traditional techniques.

Analysis of paralytic shellfish toxins using a HPLC single step-gradient method with products of post-column derivatization detected using a fluorescence detector

This application note outlines the performance benefits achieved with UCT’s LipiFiltr® cleanup cartridge for the analysis of pesticides in oil-based cannabis products using LC–MS/MS analysis.

Abuse of synthetic opioid prescription painkillers such as fentanyl, along with a rapidly growing list of illicit analogues, is a significant public health problem. In this study, we developed a simple dilute-and-shoot method that provides a fast 3.5-min analysis of fentanyl and related compounds (norfentanyl, acetyl fentanyl, alfentanil, butyryl fentanyl, carfentanil, remifentanil, and sufentanil) in human urine by LC–MS/MS using a Raptor Biphenyl column.