Kate Jones

This collection of technical articles, interviews, and news pieces delves into the latest innovations in LC methods, including advance in high performance liquid chromatography (HPLC), ultrahigh-pressure liquid chromatography (UHPLC), liquid chromatography–mass spectrometry (LC–MS), and multidimensional LC.

Brett Paull has been awarded the Premier’s Tasmanian STEM Researcher of the Year for his outstanding contributions to analytical chemistry.

A liquid chromatography–tandem mass spectrometry (LC–MS/MS) method to enhance dicarboxylic acid (DCA) detection and quantification in different biological matrices has been developed and optimized.

The Chromatographic Society (ChromSoc) has announced the winners of the Martin Medal and the Silver Jubilee Medal for 2025. Professor Bogusław Buszewski of Nicolaus Copernicus University in Torun, Poland, has been awarded the prestigious Martin Medal, and the 2025 Silver Jubilee Medal has been awarded to Elia Psillakis of the Technical University of Crete in Greece.

Three analytical and two pre-treatment methods—gas chromatography–mass spectrometry (GC–MS), gas chromatography–tandem mass spectrometry (GC–MS/MS), and liquid chromatography–tandem mass spectrometry (LC–MS/MS) plus liquid-liquid extraction (LLE) and dried blood spot (DBS) —were compared for the quantitation and characterization of barbiturates.

The volatile organic compounds (VOCs) that make up the flavor profile of cigars are examined using gas chromatography (GC) and E-nose.

This month we interview Shijia Tang, principal scientist at Genentech, South San Francisco, CA, USA, about her innovative research focusing on the analysis of polymers and nanomaterials used in pharmaceutical analysis. Shijia decribes the benefits of an innovative in-line mixing modulation method for 2D-LC she developed for polymer and oligonucleotide analysis. The advantages of SEC–MALS to explore aggregation mechanisms for therapeutic constrained peptides and mRNA-lipid nanoparticles and their aggregates are also discussed.

This month we spoke to Zhuoheng Zhou from the Vrije Universiteit Brussel in Belgium about his research on advancing instrumental and column technologies for modern chromatography and its applications in novel biopharmaceutical modalities and proteomics.

LCGC spoke to Leandro Wang Hantao from the University of Campinas in São Paulo, Brazil, about his work investigating the influence of ion management parameters on the data produced by comprehensive gas chromatography–high-resolution mass spectrometry (GC×GC–HRMS) equipped with a fourier transform-orbital ion trap mass analyzer, and his investigation into employing channel occlusion for sample preparation in untargeted analysis in petroleomics.

The Column spoke with Ilaria Belluomo from Imperial College London, UK, about her research in breath analysis. She details her work into a noninvasive breath test that can be used to detect colorectal cancer using GC–MS. She also discusses the use of SIFT-MS for the analysis of VOCs in breath.

This month we interview Zhuoheng Zhou from the Vrije Universiteit Brussel in Belgium, about his focus on advancing instrumental and column technologies for modern chromatography and its applications in novel biopharmaceutical modalities and proteomics. We also spoke to him about his work developing a protocol to help with the design of polymer monolithic capillary columns.

We spoke with Ibraam Mikhail, a postdoctoral research fellow (analytical chemistry) at the Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Australia, about his work developing a multiwavelength absorbance detector that uses pulsed-deep ultraviolet light-emitting diodes (DUV-LEDs), and how this detector performs compared to other standard detectors.

This month we interview Selina Tisler from the University of Copenhagen, Denmark, about her work using supercritical fluid chromatography (SFC) to detect very polar compounds and compounds of unknown toxicity in wastewater effluents, and her recent investigation into the migration of compounds from reusable plastic bottles into drinking water using a nontargeted screening approach.

ISSS 2023 and other important events for chromatographers.

Talks by Dwight R. Stoll, Tadeusz Górecki, André de Villiers, and Andrea Gargano highlighted the after-lunch presentations at HPLC 2023 on June 20.

This month we interview Leo Wang Hantao from the University of Campinas in São Paulo, Brazil, about his work investigating the influence of ion management parameters on the data produced by comprehensive gas chromatography–high-resolution mass spectrometry (GC×GC–HRMS) equipped with a fourier transform-orbital ion trap mass analyzer, and his investigation into employing channel occlusion for sample prep in untargeted analysis in petroleomics.

This month we interview Juan L. Benedé from the University of Valencia in Spain, about his work developing microextraction approaches, based on the use of sorbent materials, for application to complex matrices, and his focus on the determination of disease biomarkers in biofluids.

This month we interview Petr Vozka from the California State University in Los Angeles, USA, about his work developing methods for analyzing products from plastic waste conversion processes and organic compounds adsorbed on microplastics using two-dimensional gas chromatography (GC×GC).

This month we interview Anele Mpupa from the University of Johannesburg in South Africa, about his work in sample preparation using liquid chromatography with mass spectrometry (MS), and his particular focus on water quality monitoring.

The Column interviewed Varoon Singh from the National Dope Testing Laboratory in India, about his work in sample preparation using chromatography with mass spectrometry (MS), and the development of novel materials for analytical applications.

This month we interview Martina Catani from the University of Ferrara, Italy, about her work on the separation of enantiomers by high performance liquid chromatography/ultrahigh-pressure liquid chromatography (HPLC/UHPLC) and the study of the kinetic and thermodynamic properties of chiral stationary phases, and the separation and purification using LC analysis (single-column and continuous multi-column) of biomolecules of high therapeutic interest.

The Column interviewed Maiken Ueland, an ARC discovery early career research fellow at the Centre for Forensic Science and deputy director of The Australian Facility for Taphonomic Experimental Research (AFTER) at the University of Technology Sydney in Australia, on her work in forensic taphonomy, where she uses analytical, biochemical, and spectroscopic techniques to conduct human post-mortem investigations.

This month we interview Raviraj Chandrakant Shinde from India, about his work on the analysis of various food contaminants using chromatography and mass spectrometry, and the challenges involved in analyzing polar and ionic pesticides.

This month we interview Jessica Pandohee about her work in foodomics in prebiotics research for gut health, and the role of GC–O in aroma analysis for coffee-flavoured milk.

A snapshot of key trends and developments in sample preparation according to selected panellists from the chromatography sector.

This month we interview Simona Felletti, a postdoctoral researcher in analytical chemistry in the Department of Chemical, Pharmaceutical and Agricultural Sciences at the University of Ferrara, Italy, about her work in the mass transfer phenomena and thermodynamic properties of packed columns under both LC and SFC conditions, and the hazardous potential that uncharacterized minor cannabinoids pose.

A snapshot of key trends and developments in GC/GC–MS according to selected panellists from the chromatography sector.

This month we interview Natalia Manousi, from the Laboratory of Analytical Chemistry at the Department of Chemistry of the Aristotle University of Thessaloniki in Thessaloniki, Greece, about her work in the development and application of novel sample preparation techniques.

This month we interview Sara Carillo, Bioanalytical Research Lead at NIBRT, about her work developing new analytical approaches in biopharma, what attracted her to this research, and the benefits of a multi-attribute method (MAM) workflow in her work.

This month we interview Alexandre Goyon, Senior Scientist in the Small Molecule Pharmaceutical Sciences Organization of Genentech, about his work focused on the online digestion and analysis of RNA molecules using immobilized RNase cartridges attached to a mDLC–MS system, and why the accurate sequencing of sgRNA is important.