SPE of Lipophilic Marine Biotoxins
June 1st 2009A research group from NRL Marine Biotoxins, Federal Institute for Risk Assessment (Berlin, Germany) developed a solid-phase extraction (SPE) method for the enrichment and clean-up of lipophilic marine biotoxins from various species of bivalve molluscs and processed shellfish products.
Dispersive Liquid-Phase Microextraction of Aromatic Amines in Water
June 1st 2009Scientists from Henan Normal University (Xinxiang, China) and the University of Science and Technology Beijing (Beijing, China) developed an ultrasound-assisted ionic liquid dispersive liquid-phase microextraction procedure for determining four aromatic amines in water samples.
Mass Spectrometry in Homeland Protection
June 1st 2009For those of you who have not yet had a chance to read Spectroscopy and LCGC?s "Homeland Security" supplement (www.spectroscopyonline.com), Tuesday morning's "Mass Spectrometry in Homeland Protection" session should provide a nice overview of the topic.
Welcome again, to Day 2 of ASMS 2009
June 1st 2009Welcome again, to Day 2 of ASMS 2009. We?re pleased to bring you our continued coverage from Philadelphia, Pennsylvania. ASMS is in full swing, and last night?s hospitality suites were as crowded as ever, as you might imagine. Tonight promises to be another crowded night at the Marriott, but before then, there is a whole day of mass spectrometry-related science.
Mass Spectrometry and Biofuels, Ballroom A
June 1st 2009The call for increased biofuel production will surely be closely followed by a need for improved methods of analysis. The six presentations in this Tuesday morning session will examine various roles of mass spectrometry in biofuels analysis and will cover topics such as biodiesel characterization, metaproteomic analysis of termite microbes relevant to biofuel development, and multiple reaction monitoring of biofuels systems metabolic pathways.
USP <1058> Analytical Instrument Qualification and its Impact on the Chromatography Laboratory
June 1st 2009United States Pharmacopeia (USP) general chapter 1058 on analytical instrument qualification (AIQ) has finally become official and was released in August 2008 in the first supplement to the USP XXXI.1 This column reviews AIQ and discusses the impact it will have in the regulated chromatography laboratory.
Evaporation-Free Extraction and Application in High-Throughput Bioanalysis by LC–MS-MS
June 1st 2009Evaporation-free extraction (no drying down) is highly desirable because of its reduced cost and pollution, higher speed, and less possibility for contamination and conversion. Presented in this article are four types of evaporation-free extraction that are widely applicable. The first one is for the determination of didanosine over the range of 25.02–2502.00 ng/mL by injecting solid-phase extraction (SPE) eluate directly. The second is for the determination of betamethasone phosphate over the range of 2.51–250.60 ng/mL by injecting SPE eluate after pH adjustment. The third is for the determination of sumatriptan over the range of 0.99–99.40 ng/mL based upon SPE with high organic washing and low organic elution. The fourth is based upon automated dilution after protein precipitation for the determination of raloxifene-4'-glucuronide and raloxifene-6-glucuronide over the ranges of 2.02–202.40 ng/mL and 0.40–39.95 ng/mL, respectively.
Accurate Mass LC-MS Approaches for Characterization and Quantification of Drugs and Metabolites
June 1st 2009A session dedicated to "Accurate Mass LC-MS Approaches for Characterization and Quantification of Drugs and Metabolites" will kick off the fourth day of the technical program on Tuesday at the 57th ASMS Conference in Philadelphia, Pennsylvania.