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Instant column connector for capillary gas chromatography-NLISIS Application Note

Small-scale Purification using SFC ELSD -Thar Application Note

Since the USA Patriot Act* has been enacted, many pharmaceutical companies have reformulated their over the counter (OTC) drug products with phenylephrine (a nasal decongestant) as a substitute for pseudoephedrine.

Joining us for this discussion are Nelu Grinberg of Boehringer Ingelheim Pharmaceuticals, Inc.;Todd Palcic of TharSFC, a Waters Company; and Jelena Kocergin of Regis Technologies, Inc.

Analysis of Bumetanide-Varian Application Note

Determination of Phthalate-Varian Application Note

Owlstone Nanotech and Agilent Technologies have announced a phase one agreement to develop Owlstone's field-asymmetric ion mobility spectrometry (FAIMS) filter as a front-end separation module for Agilent's Accurate Mass time-of-flight mass spectrometers (TOF-MS).

Sugar alcohols require unique methods for analysis by HPLC due to their high polarity and lack of a UV-absorbing chromophore. USP methods for these separations take advantage of ion exclusion HPLC techniques. In this note, several different separations of sugar alcohols were performed us­ing ion exclusion Rezex RPM and RCU HPLC columns.

PerkinElmer and LEAP Technologies have entered into a resale agreement for ultra high performance liquid chromatography (UHPLC) and high performance liquid chromatography (HPLC) technology.

Glyphosate: Retention of Extremely Polar Compounds-Microsolv Application NOte

The answer to the following reader question about degassing mobile phase solvents was supplied by LCGC's "LC Troubleshooting" columnist John Dolan.

Sugar alcohols such as mannitol, sorbitol, and xylitol are often used as fillers to increase the bulk volume of pharmaceutical tablets because of their inert properties and sweet taste.

Varian, Inc. has published an application note entitled Analysis of Albumin Proteins using ProSEC 300S Columns.

The most difficult problem for an investigator in chiral separations is to determine where to start. Cost considerations, availability of equipment, and know-how play important roles in the selection process (1,3-5).

The FMS Power-Prep? EPH Fractionation system performs fractionation and sample clean-up for up to 30 samples in less than 1 hour, producing the highest recoveries and best results for aliphatic and aromatic hydrocarbon content.

The new European headquarters of the Yokogawa Electric Corporation have officially been opened in Amersfoort, the Netherlands, at a ceremony attended by public dignitaries and senior Yokogawa management.

LCGC's coverage of ASMS 2009, day three, from Philadelphia.

LCGC's coverage of ASMS 2009, day two, from Philadelphia.

The environment and possible contaminants will take center stage in a Wednesday afternoon session at the 57th annual ASMS Conference in Philadelphia, Pennsylvania.

Fossil fuels are a limited resource, and the petroleum industry is always on the lookout for ways to extract more useful materials from crude oil. This session focuses on the use of mass spectrometry in the analysis of petroleum.

Monitoring Protein Deamidation by Cation-Exchange Chromatography-Dionex Application Note

Wednesday afternoon's session titled "MS of Polymers/Materials II: HPLC and Ion Mobility Separation" is part II of Wednesday morning session, "MS of Polymers/Materials I: Structures and Properties." The second half of this session will pick up where part one left off and address additional topics involving HPLC and other applications.

Chromatographic Fingerprinting of Flos Chrysanthema Indici-Dionex Application Note

Ion mobility spectrometry has found commercial success as a homeland security tool in the field detection of explosives, drugs, and chemical weapons. Other common uses for the technique have been in the pharmaceutical industry for cleaning validation and in the analysis of biological material. The applications to be discussed in this Wednesday morning session include the combination of IMS with MS, the characterization of carbohydrate?protein binding, protein and peptide analysis, IMS-MS analyses with elevated electric field intensities, and neutral ion pair evaporation from ionic liquid nanodroplets

It's hard to believe these three days have gone by so quickly, but here we are on the last day of this week's show coverage

This column reviews AIQ and discusses its impact in the regulated chromatography laboratory.

LCGC's coverage of ASMS, day one, from Philadelphia.

Waters Corporation (Milford, Massachusetts) announced that the U.S. Drug Enforcement Administration has purchased a Waters ACQUITY UltraPerformance liquid chromatograph for use in training new forensic chemists at the agency's Special Testing and Research Laboratory in Dulles, Virginia.

High Throughput SEC of Water Soluble Polymers Using TSK-GEL SuperAW Columns-Tosoh Application Note

Separation of IgM using TSK-GEL BioAssist S -Tosoh Application Note