All News

Steroid testing is commonly associated with sports doping testing to monitor athletes for performance-enhancing compounds, but it also important in the food industry for consumer safety. A new method using high-temperature liquid chromatography with photodiode detection and isotope ratio mass spectrometry (HT?LC?PDA?IRMS) that does not require sample derivatization and uses water as the eluent has been developed by scientists at the University of Duisberg-Essen in Essen, Germany.1

This Monday afternoon session will be chaired by Koji Otsuka of Kyoto University, in Japan.

In today?s program, Ron Majors of LCGC, Fabrice Gritti of the University of Tennessee, and David S. Bell of Supelco/Sigma-Aldrich will each present a free tutorial session.

In today?s free tutorials, several very practical topics will be covered, including theoretical and practical aspects of UHPLC, the role of dwell volume in UHPLC method transfer, and how regulations are changing the role of separation sciences

Fabrice Gritti of the University of Tennessee in Knoxville, Tennessee, will preside over this Tuesday morning session.

Jonathan Sweedler of the University of Illinois in Champaign, Illinois, will chair this Monday morning session.

Past, present, and future developments of supercritical fluid extraction (SFE) are outlined. New vendor activity in terms of automation and hyphenation with chromatographic separations is discussed.

This article introduces some of the concepts behind green chemistry, covering solvent selection and extraction techniques.

The current status of superheated water extraction is reviewed, and the extraction methods, applications, and problems encountered are discussed.

Current advances in commercial pressurized-fluid extraction (PFE) instrumentation are discussed, along with the advantages of performing PFE prior to chromatographic analysis.

The author reviews the automation capabilities available, and some practical considerations to take into account when choosing to automate some or all of the sample preparation and handling steps that must be done before analysis.

This month's "LC Troubleshooting" instalment looks at two reader-submitted questions regarding method calibration.

Microwave-accelerated extraction (MAE) is described and evaluated. The latest enhancements to this technology are discussed from a hardware and applications perspective.

The session chair for this Wednesday afternoon session is Chao Yan of Shanghai Jiao Tong University (China). The session will be held in room HEC-C in the Hilton Exhibition Center on the second floor of the Hilton, beginning at 1:30 p.m.

Emily Hilder of the University of Tasmania (Australia) - and LCGC Editorial Advisory Board member - will chair this Monday morning session in room HEC-A, Hilton Exhibition Center (second floor of the Hilton). The session will begin at 9:00 a.m.

This Wednesday afternoon session will cover several interesting ways that LC?MS techniques are applied to biological applications. This session will begin at 1:30 p.m. and conclude at 3:00 p.m. Sarah Trimpin of Wayne State University in Detroit, Michigan will chair the session.

This Tuesday morning session will cover some new advances in ultra-high pressure liquid chromatography (UHPLC). The session will start at 8:30 a.m. and conclude around 10:00 a.m. The session will be chaired by Monika Dittmann of Agilent Technologies in Germany.

This Tuesday afternoon session will be chaired by Martin Gilar of Waters Corporation (Milford, Massachusetts) and will be held in room HEC-A of the Hilton Exhibition Center on the second floor of the Hilton. The symposium will begin at 1:30 p.m. with the presentation of the Uwe Neue Award.

Microwave-accelerated extraction (MAE) is described and evaluated. The latest enhancements to this technology are discussed from a hardware and applications perspective.

Click the title above to open the LCGC Europe May 2014 Recent Developments in Sample Preparation Supplement, Vol 27 No s5, in an interactive PDF format.

New GC columns, SFC columns, and products for sample preparation, including small benchtop instruments

Part 2 of our yearly report on new products introduced at Pittcon. This instalment of "Column Watch" covers GC columns, SFC columns, and products for sample preparation including small benchtop instruments.

This month's "LC Troubleshooting" instalment looks at two reader-submitted questions regarding method calibration.

Event News

In this study, the quality-by-design principle is applied instead of trial-and-error in the development of a liquid chromatography (LC) method. A mixture of an active pharmaceutical ingredient and its 13 impurities was analyzed on a short narrow-bore column (50 mm ? 2.1 mm, packed with sub-2-?m particles) providing short analysis times. The performance of commercial modelling software for robustness testing was systematically compared to experimental measurements and design-of-experiment–based predictions.

This study presents results of gel permeation chromatography (GPC) and analytical temperature rising elution fractionation (TREF) of polyethylene in butylal (dibutoxymethane, a halogen-free solvent).

A multi-residue method has been developed and validated for the analysis of methylxanthines (caffeine and its metabolites) and cotinine in human plasma. The method has been successfully applied to the analysis of 500 samples from pregnant women in a clinical study.

The power of MS-MS analysis applied to GC analysis, including the instrumentation, experiment types, and application areas

A team of scientists in Portugal and Spain have performed high performance liquid chromatography coupled with fluorescence detection (HPLC– FLD) to show that marinating pork meat in beer can reduce the levels of polycyclic aromatic hydrocarbons (PAHs) formed when grilled over charcoal.

Barry L. Karger, founding director of Northeastern University?s Barnett Institute of Chemical and Biological Analysis (Massachusetts, USA), has received the Arnold O. Beckman Award for Outstanding Scientific Achievements for his work in electrodriven separation techniques, sponsored by Sciex Separations, a division of AB Sciex (Massachusetts, USA).