This Monday afternoon session will be chaired by Koji Otsuka of Kyoto University, in Japan.
5C, Monday Parallel Session: Stationary Phase Design I
Room HEC-C, Hilton Exhibition Center, 2nd floor
This Monday afternoon session will be chaired by Koji Otsuka of Kyoto University in Japan.
The session will begin with a presentation by David McCalley of University of the West of England in Bristol, UK, titled “New Developments in Hydrophilic Interaction Chromatography.”
Brett Paull of the University of Tasmania in Hobart, Australia, will follow McCalley’s presentation with a talk titled “Combining Mixed-mode and HILIC Based Chromatography in Comprehensive Pharmaceutical Analysis. Single Column and Parallel Column Approaches.”
Following Paull will be Andrea Gargano of the Van’t Hof Institute for Molecular Sciences in Amsterdam, The Netherlands. Gargano’s talk is titled “Mucin-based Stationary Phases as Tool for the Characterization of Drug-Mucus Interaction.”
The final talk of this session will be given by David Hage of the University of Nebraska in Lincoln, Nebraska. Hage will speak on “Personalized Medicine by High-Performance Affinity Chromatography: Recent Developments in Affinity Microcolumns and the Analysis of Complex Biological Interactions.”
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January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.