October 29th 2024
Manitoba Centre for Proteomics and Systems Biology scientists produced a new means of predicting peptide retention times for hydrophilic interaction liquid chromatography (HILIC) at acidic pH in formic-acid based eluents.
Two Dimensional Liquid Chromatography: A Powerful Tool for The Characterization of Humic Substances
October 17th 2011Analysis of natural compounds is becoming increasingly important. One thriving area is the evaluation and application of environmental biopolymers, such as humic substances (HSs) in various applications, including medicine, industry, agriculture and environmental protection.
Accelerating Proteomic Biomarker Validation
October 7th 2011The optimum in proteomics research today is in validating the performance of promising biomarkers across large biological sample sets. Many new strategies have been developed in recent years to improve and accelerate targeted MS verification assays.
CESI–MS: An Essential Complement to Nano LC–ESI–MS for Complex Proteome Analysis
October 7th 2011Liquid chromatography–electrospray ionization–mass spectrometry (LC–ESI–MS) is often used for the identification of proteins from complex peptide mixtures made from enzymatic digests of selected proteomes.
Determination of α-Amanitin in Human Serum by Solid-Phase Extracton Coupled with HPLC-UV
August 1st 2011A method is presented for the determination of ?-amanitin, a toxic cyclic octapeptide of amanitin mushrooms, in human serum by solid-phase extraction coupled with high performance liquid chromatography with UV detection.