Method Development for Fast Separation of Polycyclic Aromatic Hydrocarbons Using Micro-LC - The Importance of the Dwell Volume
The Column
This article will shed some light on recent developments of micro-LC and the possibility of applying fast separations while reducing toxic and costly solvent waste.
Over the years there has been an on-going trend for miniaturization in life sciences. There is a similar trend in the field of chromatography. Some manufacturers have already introduced new devices on the basis of chip‑technology. Unfortunately, progress is very slow and many users are searching for “bridge technologies” like micro-LC. Although the instrumentation has matured, many practitioners are still prejudiced against micro‑LC because of long-standing notions of irreproducible gradient formation and a low robustness of commercially available instruments. This article will therefore shed some light on recent developments of micro‑LC and the possibility of applying fast separations while reducing toxic and costly solvent waste.
Inside the Laboratory: The Zydney Group at Pennsylvania State University
November 26th 2024In this edition of “Inside the Laboratory,” Andrew Zydney of Pennsylvania State University discusses his laboratory’s work with using high performance liquid chromatography (HPLC) to analyze biopharmaceutical products before and after membrane separation processes.
Green Chemistry: What is it (and What Is It Not)? And How Does It Apply to Gas Chromatography?
October 31st 2024Everyone is talking about sustainability, and organizations are creating sustainability programs. But what does green chemistry really mean, and how does it apply to gas chromatography?
