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F Kribbel

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Articles

Using MS Data for Peak Tracking in Computer Supported HPLC Method Development

Using MS Data for Peak Tracking in Computer Supported HPLC Method Development

F Kribbel;K E Monks;Bjoern-Thoralf Erxleben;Hans-Jürgen Rieger;Imre Molnar
February 1st 2012

A systematic way to develop HPLC methods consists of building up and running a useful set of experiments (DOE, design of experiments) to evaluate the influence of several factors or method conditions on the selectivity of a chromatogram. The crucial part here is the peak tracking between the chromatograms.

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