Real-Time, Broad-Spectrum Odor Analysis Using SIFT-MS
March 1st 2016The sensitive, selective, and real-time analysis characteristic of the SIFT-MS technique provides simple, robust, and continuous analysis of extremely diverse odor compounds at trace levels in air. This application note illustrates instantaneous, broad spectrum odor analysis with monitoring data from a chicken meat production facility.
Nontargeted Metabolite Profiling in Next-Generation Plant Breeding: A Case Study in Malting Barley
March 1st 2016The power of nontargeted metabolite profiling is illustrated in a study focused on the determination of molecular markers in malting barley that are predictive of desirable malting quality for brewing applications.
Extraction and Quantification of Mycotoxins in Peanut Butter Using SFE–SFC–MS
February 22nd 2016Aflatoxins are poisonous and carcinogenic chemicals that occur in nature in soil, hay, and grains. When contaminated food is processed, aflatoxins can enter the general food supply chain and can be dangerous for humans and animals. Time- and cost-efficient analytical methods can ensure food safety. Compared to conventional manual methods the use of “supercritical” CO2 for supercritical fluid extraction (SFE) as well as chromatographic separation (supercritical fluid chromatography [SFC]) of aflatoxins offers a more efficient process while reducing solvent consumption.
Discovering the Drug Habits of Nightclubbers and Criminals Using UHPLC
February 22nd 2016The Norwegian Institute of Public Health conducted a study into the drug use habits of nightclubbers and arrested criminals in Oslo, Norway. The study used UHPLC–MS–MS to analyze the drug-use profiles of nightclubbers and criminals arrested while under the influence of drugs to develop an understanding of drug use patterns in these groups.
Sciex Joins with Children’s Medical Research Institute to Advance Proteomic Profiling
February 22nd 2016Sciex has announced it is teaming up with the Children’s Medical Research Institute to help equip The Australian Cancer Research Foundation International Centre for the Proteome of Cancer facility with tools to advance its large‑scale proteomic profiling studies.
Compositional Analysis of Honeybee Venom for Proteomics
February 22nd 2016Research into honeybee venom is being performed to identify active proteins acting as allergens and toxins. Researchers combined LC–MALDI-TOF/TOF-MS–MS, LC–ESI-QTOF-MS–MS, and a combinatorial peptide ligand library enrichment method to detect 269 proteins.
The Chromatographic Society’s: Advances in Microcolumn and Related Separation Technologies
February 22nd 2016The first meeting of The Chromatographic Society’s Diamond Jubilee celebration year will be held at the Institute of Engineering and Technology (IET) in Savoy Place, London, UK, on Tuesday 22 March 2016.
VUV Analytics in Collaborative Project with Caltech Environmental Analysis Center
February 19th 2016VUV Analytics (Cedar Park, Texas) is collaborating with Caltech Environmental Analysis Center (EAC) in Pasadena, California, in a closed-ended project that explores new application capabilities using VUV’s VGA-100 Vacuum Ultraviolet (VUV) detector.
Quantifying Methylergonovine Using LC–MS–MS
February 18th 2016A team of researchers from China and the USA has developed a liquid chromatography coupled to tandem mass spectrometry (LC–MS–MS) method for quantifying methylergonovine (ME), a semi-synthetic ergot alkaloid used for the treatment and prevention of postpartum haemorrhage (PPH), in human plasma.
Tips & Tricks GPC/SEC: Upside Down — Inverse GPC for Pore Size Distributions
February 8th 2016Gel permeation/size-exclusion chromatography (GPC/SEC) is the standard method for separating samples by molecular size and determining molar mass distributions. However, GPC/SEC instruments can also be used to investigate porous materials and to learn more about pore size distributions, as a powerful alternative to nitrogen gas (N2) adsorption or mercury (Hg) intrusion porosimetry.
A Collaborative Approach to Water Analysis
February 8th 2016Contaminants in surface water and drinking water supplies arising from pharmaceutical and personal care product use as well as other compound sources pose a difficult challenge for analytical chemists. Thomas Letzel from the Technical University of Munich in Germany, spoke to The Column to discuss collaborative research taking place in Europe to address contaminants of emerging concern in water analysis.
Detection Markers in Trypanosomiasis
February 8th 2016Researchers from Imperial College London and the University of Aberdeen have identified disease markers for Human African Trypanosomiasis (HAT), commonly known as “sleeping sickness”. Using reversed-phase ultrahigh‑performance liquid chromatography coupled to mass spectrometry (UHPLC–MS) and proton nuclear magnetic resonance (1H NMR) spectroscopy researchers found 53 discriminatory metabolite markers.