Wednesday Parallel Session: High Resolution Liquid Chromatography, Mass Spectrometry, and Ion Mobility Spectrometry (LC, MS, and IMS) - I
The session chair for this Wednesday afternoon session is Emily Hilder of the University of South Australia. The session will be held in the Golden Gate Ballroom C, floor B2 level, beginning at 1:30 p.m.
The session chair for this Wednesday afternoon session is Emily Hilder of the University of South Australia. The session will be held in the Golden Gate Ballroom C, floor B2 level, beginning at 1:30 p.m.
This session’s first presentation is a keynote lection that will be given by Richard Smith of Pacific Northwest National Laboratory. The title of Smith’s presentation is “Ultrahigh Resolution and Ultrasensitive Ion Mobility Separations with MS Using Structures for Lossless Ion Manipulations.”
The next presentation in the session is a second keynote lecture titled “High Resolution and Ion Mobility Mass Spectrometry for Multidimensional Separations in -Omics” and will be presented by Gerard Hopfgartner of the University of Geneva.
The penultimate presentation of the session will be presented by Chunang (Christine) Gu of Genentech. The title of Gu’s presentation is “Structural Elucidation Challenges when 2D-HPLC Meets Mass Spectrometry.”
Lihua Zhang of the Dalian Institute of Chemical Physics at the Chinese Academy of Sciences will present the final talk in this Wednesday session. The presentation is titled “Quantitative Analysis of Proteomic Samples by Novel LC-MS/MS Based Methods.”
The session will be followed by Poster Session 4 in the Yerba Buena Ballroom Exhibition Hall, floor lower B2 level (poster presentations: Emerging Separation Techniques; Environmental and Energy-Related Analysis; Method Development and Automation; Protein Characterization, Modifications and Protein Binding; and Quality by Design [QbD] and Design of Experiment [DOE]).
Detecting Hyper-Fast Chromatographic Peaks Using Ion Mobility Spectrometry
May 6th 2025Ion mobility spectrometers can detect trace compounds quickly, though they can face various issues with detecting certain peaks. University of Hannover scientists created a new system for resolving hyper-fast gas chromatography (GC) peaks.
University of Oklahoma and UC Davis Researchers Probe Lipidomic Profiles with RP-LC–HRMS/MS
May 6th 2025A joint study between the University of Oklahoma Health Sciences Center (Oklahoma City, Oklahoma) and the UC Davis West Coast Metabolomics Center (Davis, California) identified differentially regulated lipids in type 2 diabetes (T2D) and obesity through the application of reversed-phase liquid chromatography-accurate mass tandem mass spectrometry (RP-LC-accurate MS/MS).
Automated Sample Preparation (ISO 20122) for MOSH/MOAH in Seasoning Oils
May 6th 2025This work presents an Automated Sample Preparation procedure for MOSH/MOAH analysis of Seasoning Oils. We compare results from a manual epoxidation procedure compliant with DIN 16995 with results based on fully automated sample preparation (epoxidation and saponification) compliant with ISO 20122. In both cases, online clean-up via activated aluminum oxide (AlOx) are used to remove interfering n-alkanes from the MOSH fraction during the HPLC run. Automated data evaluation using a dedicated software (GERSTEL ChroMOH) is presented.
