Gases for Electron-Capture Detection
April 6th 2010What do you advise using as gases with electron-capture detection (ECD) for gas chromatography? Would it be better to purchase higher quality gases or to place an oxygen trap between the gas bottle and the detector? Which setup would be the most cost-effective?
Current Progress in Chiral Stationary Phase Development and an Update of Chiral Applications
April 1st 2010This discusses using generic chiral stationary phase screening to find the optimum column, smaller diameter columns for HPLC and SFC, clones of off-patent phases, and new concepts in CSP development.
HPLC Column Technology: State-of-The-Art
April 1st 2010Improvements in HPLC column technology continue. Since the last Special Supplement on columns in 2008 (1), the continued need for high-throughput separation, the encountering of more complex samples, the need to analyze very polar compounds more easily, and the increased availability of very high pressure instruments has placed additional demands on the HPLC column. In terms of high throughput, no less than 24 companies have responded and have developed small particle columns of 2 µm and under. In addition, the number of superficially porous particle (SPP) columns has expanded, and users are finding that the high-efficiency-at-low-pressure advantage brings them added advantages. With more complex samples, longer columns packed with sub-2-µm particles require higher pressures with pumps now available to 1300 bar. It will be of interest to see if the lower pressure, high-efficiency SPP columns and monoliths, the latter of which have seen advances in the research of polymeric monoliths for applications to..