Digital Update
Digital Products
Continuing professional development for chromatographers
CHROMacademy is a chromatography e-learning programme that provides continuing professional development for chromatographers to make them more effective in the work place. There are over 3000 pages of e-learning on HPLC, GC, MS and Sample Preparation techniques to improve practical knowledge for the absolute novice (What is Chromatography?) to the expert who needs a refresher in a particular topic (Advanced Topics in LC-MS Spectral Interpretation, for example). The site can be also used for induction training or programmed learning activities and there are tutorials and assessments built into all learning modules to check progress. The first official webinar: Essential Guide 1: Split /Splitless Injection for Capillary GC attracted 568 visitors. The recorded session is available via the CHROMmunity at http://chrommunity.chromacademy.com (under the WEBCASTS Tab). Other Webcasts include Essential Guide 2: Mobile Phase Optimization Strategies for Reversed Phase HPLC; Essential Guide 3: Understanding and Optimizing Detectors for Capillary GC; and Essential Guide 4: Mobile Phase Optimization Strategies for Reversed Phase HPLC.
Updated digital platforms
ChromaTOF 4.30 is now available for all LECO instrument systems.New features are reported to include variable modulation times within each GC×GC chromatographic run for a more specialized analysis, which maximizes resolution in both the first and second dimensions. Also available is the LECO/Fiehn metabolomics library with over 1100 spectra of 700 unique metabolomics for metabolite identification of the most complex samples. Fully integrated within the system, the library works seamlessly to search for analyte matches without the need for importing or exporting data.
Chromatography software
DataApex has announced the release of Clarity version 3.0. This version is reported to bring more than 100 enhancements that increase users' comfort and add new functions, including new calibration and sequence options (such as calibration bracketing, standard addition calibration), new export into Excel format, or enhancement to GLP requirements. New control modules have been introduced so that the software can now control more than 270 different instruments from one environment. Users can download the latest version from DataApex webpages. The detailed list of changes in the new version is available from the company's webpages for easy navigation in the new version.
Integrated software and database
Bio-Rad has released a fully integrated software and database package to provide multiple tools, including database building and management, search, analysis, structure drawing and reporting within a single user interface. According to the company, the KnowItAll Informatics System 8.2 includes a series of new report templates for more efficient output and improved design and a function to preview chromatograms and spectra to be used for searching, interpretation or database creation before the file is actually opened. The informatics system is reported to offer a fully integrated environment with flexible and expandable software and database solutions for chromatography, MS, cheminformatics; chemometrics, metabolomics and more.
New Study Uses MSPE with GC–MS to Analyze PFCAs in Water
January 20th 2025Scientists from the China University of Sciences combined magnetic solid-phase extraction (MSPE) with gas chromatography–mass spectrometry (GC–MS) to analyze perfluoro carboxylic acids (PFCAs) in different water environments.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ion used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
A Guide To Finding the Ideal Syringe and Needle
January 20th 2025Hamilton has produced a series of reference guides to assist science professionals in finding the best-suited products and configurations for their applications. The Syringe and Needle Reference Guide provides detailed information on Hamilton Company’s full portfolio of syringes and needles. Everything from cleaning and preventative maintenance to individual part numbers are available for review. It also includes selection charts to help you choose between syringe terminations like cemented needles and luer tips.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Oasis or Sand Dune? Isolation of Psychedelic Compounds
January 20th 2025Magic mushrooms, once taboo, have recently experienced a renaissance. This new awakening is partially due to new findings that indicate the effects of psilocybin, and its dephosphorylated cousin psilocin may produce long lasting results for patients who might be struggling with anxiety, depression, alcohol and drug abuse, and post-traumatic stress disorder. Hamilton Company has developed a methodology for the isolation and identification of 5 common psychedelic compounds used in the potential treatment of disease. The PRP-1 HPLC column resin remains stable in the harsh alkaline conditions ideal for better separations.
