March 21st 2025
LCGC International spoke with Daniel Meston and Dwight Stoll from Gustavus Adolphus College in St. Peter, Minnesota, USA, about a project they worked on with Todd Maloney from Eli Lilly in Indianapolis, Indiana, USA, to investigate the optimal performance conditions of antisense oligonucleotides (ASOs) when using hydrophilic interaction liquid chromatography (HILIC).
Separation Science — The State Of The Art in Life Science Analysis: A Virtual Symposium
September 26th 2024Webinar Date/Time: Wednesday, October 23rd, 2024 Morning Session: 14:30 pm BST | 9:30 am EDT | 15:30 pm CEST Afternoon Session: 16:30 pm BST | 11:30 am EDT | 17:30 pm CEST Thursday, October 24th, 2024 Morning Session: 14:30 pm BST | 9:30 am EDT | 15:30 pm CEST Afternoon Session: 16:10 pm BST | 11:10 am EDT | 17:10 pm CEST
Rapid Quantitative Analysis of Ethylene Oxide and 1,4-Dioxane in Polymeric Excipients Using SIFT-MS
Pharmaceutical excipients, such as polyethylene glycol-based polymers, must be tested for the presence of ethylene oxide (EtO) and 1,4-dioxane as part of a safety assessment, according to USP Chapter <228>.
Self-Cleaning LC–MS in Organoid/Organ-on-Chip Systems for Small Molecule Analysis
August 7th 2024Steven Ray Wilson and Hanne Røberg-Larsen of the University of Oslo recently discussed the practical application and advantages of their FDA-validated research to analyse small molecule drugs and their metabolites in organoid/organ-on-chip systems that serve as alternatives to animal models.
Characterization of Product Related Variants in Therapeutic Monoclonal Antibodies
July 16th 2024Navin Rauniyar and Xuemei Han of Tanvex Biopharma USA recently discussed how identifying product-related variants through characterization enables the recognition of impurities that compromise the quality and safety of drugs.