Extractables & Leachables Screening with HRAM: Cutting-Edge Solutions for Unmatched compound Identification

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Webinar Date/Time: Wed, Oct 16, 2024 10:00 AM EDT

Join us for an insightful webinar exploring cutting-edge solutions for extractables and leachables (E&L) analysis using GC and LC Orbitrap mass spectrometry in combination with powerful software solutions to provide confident and fast compound identifcation.

Register Free: https://www.chromatographyonline.com/lcgc_w/E&L

Event Overview:


Discover Advanced Techniques in Extractables and Leachables (E&L) Screening
Join us for an insightful webinar exploring cutting-edge solutions for extractables and leachables (E&L) analysis. As therapies evolve, the need for reliable identification of extractables and leachables at lower analytical evaluation thresholds (AET) has become crucial. Traditional methods of evaluating visible peaks in chromatograms are no longer sufficient to meet these demands.


Learn how High-Resolution Mass Spectrometry (HRAM-MS) coupled with liquid and gas chromatography (LC, GC), combined with automated peak-picking algorithms, are revolutionizing E&L screening. While these technologies have been pivotal in metabolomics for over a decade, their application in E&L studies remains underutilized. Our webinar will demonstrate how leveraging these advanced tools can transform the effectiveness of E&L screening processes.


Key Learning Objectives:

  • Gain insight into state-of-the-art E&L screenings and how to achieve more accurate and reliable identification
  • Understand how advancements in the metabolomics field can be harnessed for E&L analysis
  • Learn how cutting-edge LC and GC-HRAM methods can enhance the sensitivity and selectivity of screening methods
  • Understand how these methods, together with modern deconvolution software, can be leveraged to overcome challenges of low AETs and difficult matrices

Who Should Attend:

  • Science professionals in pharmaceutical research and development
  • Analytical Chemists involved in compound identification
  • Quality control scientists in the field of extractables and leachables

Speaker:

Ulli Hohenester
Team leader E&L and HRAM Trace Analysis
SOLVIAS, Switzerland


With over 20 years of experience in mass spectrometry and structure elucidation, Dr. Ulli Hohenester is a leading expert in the field of Extractables and Leachables (E&L) analysis. Currently heading the E&L service at Solvias AG in Basel, Switzerland, Dr. Hohenester is dedicated to advancing state-of-the-art workflows that combine untargeted screening with targeted analysis. His extensive background includes expertise in small molecules, metabolites, and protein modifications, making him a key figure in the development of innovative analytical techniques at Solvias. Passionate about both the practical and theoretical aspects of mass spectrometry, Dr. Hohenester is committed to driving scientific excellence and sharing his knowledge through teaching and mentoring.

Register Free: https://www.chromatographyonline.com/lcgc_w/E&L

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