Daniel Eßer

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Daniel Eßer studied chemistry at the University of Applied Sciences Bonn Rhein-Sieg, in Rheinbach, Germany, with a focus on pharmaceutical and analytical chemistry. He received his Ph.D. in pharmaceutical and medicinal chemistry at the University of Düsseldorf, Germany. During his postdoc at the Institute of Pharmaceutical and Medicinal Chemistry of the University of Düsseldorf, he established a nanoLC–MS system. In 2013 he joined YMC Europe as a product specialist for analytical chromatography. Since 2017, he has been responsible for YMC’s analytical (U)HPLC column portfolio as product manager for analytical chromatography.

Articles

Biopharmaceuticals, capsules, close-up, black background. Generative AI | Image Credit: © dhansu - stock.adobe.com

A Study on the Optimization of the Ion-Pair Reversed Phase Liquid Chromatography Analysis of Protected And Unprotected DNA Oligonucleotides

Ann Marie Rojahn;Mathias Hehn;Daniel Eßer

July 3rd 2024

This article describes a comprehensive study on optimizing ion-pair reversed-phase liquid chromatography for analysing protected and unprotected single-stranded DNA oligonucleotides.

Image Credit: © Naeblys - stock.adobe.com

Native Anion Exchange Chromatography Coupled to Mass Spectrometry for the Charge Variant Analysis of IgG4-Based Monoclonal Antibodies

Ann Marie Rojahn;Daniel Eßer

March 6th 2024

The advantages of a native anion exchange method coupled to mass spectrometry for charge heterogeneity analysis of immunoglobulin G4 (IgG4)-based mAbs are described.