Liquid Chromatography (LC/HPLC)

This annual award is presented to an outstanding scientist in the field of chromatography.

The hyphenated method was combined with a gradient ultracentrifugation technique that allowed for lipoprotein fraction separations.

You're invited to publicize your 2023–2024 new product introductions in LCGC. Here's how to get your products included.

Scientists from Fudan University in Shanghai, China created a system for reducing retention-time variations in metabolomic analysis using ultrahigh-performance liquid-chromatography coupled with mass spectrometry (UPLC-MS).

A group of scientists from Xi’an, China have created a new system for analyzing cell membranes based around HALO-tag technology.

This month we spoke to Zhuoheng Zhou from the Vrije Universiteit Brussel in Belgium about his research on advancing instrumental and column technologies for modern chromatography and its applications in novel biopharmaceutical modalities and proteomics.

The 18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-18) will be held from 28–31 May 2024 in Leuven, Belgium.

A recent study published in the Journal of Separation Science reveals how ultrahigh-performance liquid chromatography tandem mass spectrometry (UHPLC–MS/MS) could be used to detect and quantify purine metabolites.

A novel method to simultaneously characterize the capping and poly(A) tail for therapeutic mRNA in a single sample preparation workflow is described.

There are three important habits and practices that can improve the effectiveness and efficiency of any troubleshooter.

The authors explore computer-aided workflows and machine learning, aimed at optimizing LC parameters, focusing on kinetic and thermodynamic aspects, and proposes closed-loop optimization strategies.

Understanding how approaches to degassing have evolved is helpful for troubleshooting problems with pumps and detection.

A novel LC–MS/MS method, with a dual ESI and APCI source using simple solvent extraction for sample preparation, was validated for analysis of 102 pesticides and 5 mycotoxins regulated by Colorado state in dried hemp.

This article provides a high-level overview of Current Good Manufacturing Practice (cGMP) regulations and related public quality standards.

Here, we preview the International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-18), which will be held from May 28–31st 2024 in Leuven, Belgium.

A recently published study explores and potential and limitations of reversed hydrophilic interaction liquid chromatography.

Scientists from South Dakota State University and the University of Colorado School of Medicine created a system to detect traces of cyanide in blood samples using liquid chromatography–tandem mass spectrometry (LC–MS/MS).

Chromatography is predicted to be a major player among instrument technologies, but spectroscopy and electrophoresis may also increase their market shares.

Agilent Technologies presents this award to industry leaders as a means of supporting them through financial aid, products, and expertise, along with recognition.

Two scientists from Baskent University in Ankara, Turkey analyzed multiple proteins in cream formulation using reverse-phase high-performance liquid chromatography.

Scientists from Qilu University of Technology in Jinan, China recently separated and purified components within the Phellodendron chinense plant using different types of counter-current chromatography (CCC).

This study employed an integrated method of homogenization-ultrasound-assisted extraction followed by high-speed countercurrent chromatography for efficient separation of naphthoquinones and diarylheptanes from green walnut husks.

For the first time, inhibitors of a cyclooxygenase isoform were found in Allium ampeloprasum L., specifically the giant or “elephant” garlic grown in the Chiloé Archipelago.

At EAS 2023, Michael Dong and Szabolcs Fekete reviewed certain innovations in high performance liquid chromatography (HPLC), and in what ways scientists can continue to improve the quality of their experiments.

Kennedy is a professor at the University of Michigan.

Professor Mary J. Wirth, W. Brooks Fortune Distinguished Professor Emerita at Purdue University, has been named the winner of the 2023 EAS Award for Outstanding Achievements in Separation Science.

Researchers used metabolomics analysis to measure different harvest times during the whole growing period of ligustri lucidi fructus (LLF), a traditional Chinese medicinal herb.

Scientists from Egypt have developed a green reversed-phase high-performance liquid chromatography (RP-HPLC) method to determine the amounts of methionine and paracetamol in different mixtures.

To combat fraudulent sales of low-aged ginseng disguised as high-aged ginseng, scientists from Shanghai University of Traditional Chinese Medicine created machine learning models to predict the ages of ginseng samples.

An efficient solvent system screening approach that streamlines fractionation of compounds with similar UV absorption eliminates the need for individual partition coefficient calculations, and coupled with preparative HPLC purification, led to the isolation of seven c-glycosyl flavonoids and an amino acid from barley seedlings.