LC–MS

A new RPLC–MS method can map the substitution degree and composition of β-glucose monomers of cellulose ethers (CEs), providing detailed compositional distributions and constitutional isomer distributions, thereby identifying compositional variation between bio-stable and non-bio-stable CEs and unexpected methylations in EHEC samples.

A recent trend in the design of LC instrumentation is the move towards miniaturized and portable systems.

The Chromatographic Society and the Separations Science Group of the Analytical Division of the Royal Society of Chemistry are pleased to announce Emerging Separations Technologies 2023 is to be held 24–25 May 2023, at RSC Burlington House, London, UK.

A rapid and robust LC–MS/MS method for determining lactulose and rhamnose concentrations in blood plasma was used to determine intestinal permeability from blood plasma, which can help diagnose gastrointestinal diseases such as Crohn’s disease.

This method has greater sensitivity and a shorter LC analysis time than the AOAC method. It also requires less instrument maintenance, enhances column lifetime by requiring a smaller sample volume, and reduces cost by replacing acetonitrile with methanol in the mobile phase.

Selective pressurized liquid extraction and multilayer solid‑phase extraction methods are described for high‑throughput plant, soil, and water sample preparations. Optimal analytical conditions are described for the improvement of detection sensitivities and coverage. A Source Supported Suspect Screening (4S) approach is described; phytotoxins detected in the source plant were used to improve the identification of phytotoxins in soil and water.

A new approach combining high performance liquid chromatography–mass spectrometry with ultrafiltration, along with enzyme channel blocking and directional enrichment, has been found effective for screening natural histidine decarboxylase inhibitors in Radix Paeoniae alba, while reducing both false-positive and false-negative results.

In the first of a two-part series, a recent study discusses a new strategy for assessing the peak purity of pharmaceutical peptides analysis using 2D-LC–MS.

Glyphosate and AMPA are two potentially dangerous chemicals within herbicides. Using LC–MS to detect these chemicals is important to human and environmental health.

Using LC–MS, scientists have developed a new method for testing doping steroids in blood.

Using an Analytical Quality by Design approach, scientists recently identified impurities in a pharmaceutical product for hypertension treatment.

Using liquid chromatography-tandem mass spectrometry, scientists have found a similarity between the protective functions of the oral permeability barrier and the skin barrier.

While pesticides may be beneficial, they may also cause health risks in foods. In a recent study, scientists created new methods for detecting maximum pesticide residue levels.

Dipeptide profiles have an important role in detecting disease, and a recent study has made it much more accessible to study them.

By performing tissue analysis of caracals in captivity and in their natural African habitats, scientists were able to quantify uptake of toxic chemicals from the environment depending on how polluted they are.

A recent study was conducted using liquid chromatography–tandem mass spectrometry (LC–MS/MS) to identify the effect of cooking and storage on poly)phenolic compounds in piquillo peppers.

Webinar Date/Time: Wed, May 3, 2023 11:00 AM EDT

Webinar Date/Time: Wednesday, April 26th, 2023 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST

Webinar Date/Time: Tuesday, June 6th, 2023 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST

Webinar Date/Time: Wednesday, April 19, 2023

Webinar Date/Time: Thu, Apr 20, 2023 11:00 AM EDT

Webinar Date/Time: Airing 1: Tuesday, February 28th, 2023 at 9am EST | 6am PST | 2pm GMT | 3pm CET Airing 2: Tuesday, February 28th, 2023 at 2pm EST | 11am PST | 7pm GMT | 8pm CET

Webinar Date/Time: Thursday, March 16th, 2023 at 8am PST | 11am EST | 4pm GMT | 5pm CET

Webinar Date/Time: Tuesday, January 31st, 2023 Session 1: 9am EST | 2pm GMT | 3pm CET Session 2: 2pm EST | 11am PST | 7pm GMT

Webinar Date/Time: Tuesday, February 21st, 2023 Morning session: 9:30 am EST - 12:15 pm EST Afternoon session: 2:00 pm EST - 4:00 pm EST Wednesday, February 22nd, 2023 Morning session: 9:30 am EST - 12:15 pm EST Afternoon session: 2:00 pm EST - 4:00 pm EST

Webinar Date/Time: Thu, Feb 23, 2023 11:00 AM EST

Webinar Date/Time: Wednesday, Feb 15th and Thursday, Feb 16th, 2023 Day 1: 9:00 am EST – 2:45 pm EST Day 2: 8:30 am EST – 4:30 pm EST

Webinar Date/Time: Thursday, February 16th, 2023 at 8am PST | 11am EST | 4pm GMT | 5 pm CET

Webinar Date/Time: Monday, March 27th at 11am EDT|8am PDT|4pm BST|5pm CEST

In this extended special feature to celebrate the 35th anniversary edition of LCGC Europe, key opinion leaders from the separation science community explore contemporary trends in separation science and identify possible future developments.