Advanced Materials Technology

A comparison made between a stainless steel hardware column and an INERT column using the same lot of HALO 90 Å C18, 2.7µm results in tailing factor and area improvement using the HALO®INERT column.

Using HALO®Elevate C18 and a high pH mobile phase obtains a great separation of drugs of abuse and metabolites without the use of a specialized stationary phase.

A 16 mer ssDNA poly dT oligonucleotide was analyzed under UV conditions on a HALO®OLIGO C18 column. The results revealed smaller peaks before and after the primary peak of interest.

The positively charged surface chemistry of HALO® PCS Peptide delivers narrower peak width, higher signal response and double the peak capacities compared to standard uncharged peptide materials

Over the course of 5000 injections, the HALO®Elevate C18 1.5 mm ID column demonstrates stability and robustness in the stationary phase and the column hardware, with no significant changes to the retention time, peak shape, and back pressure.

A mix of four antidepressants is separated using the HALO®PCS (positive charged surface) C18 column demonstating the improved tailing factor and efficiency when compared to a traditional (uncharged) C18 stationary phase.

The HALO® OLIGO C18 2.7 µm column outperformed an FPP Oligo C18 column in oligonucleotide separations, achieving faster separations while maintaining efficiencies comparable to a 1.9 µm FPP with more than half the backpressure.

A separation of ultra-short and long chain PFAS (C1-C18) is performed on a HALO®PCS Phenyl-Hexyl column along with a HALO®PFAS Delay column which demonstrates excellent retention for both hydrophilic and hydrophobic analytes.

Webinar Date/Time: Airing 1: Wednesday, March 20, 2024 at 11AM EDT / 3PM GMT / 4PM CET Airing 2: Wednesday, March 20, 2024 at 2PM EDT / 1PM CDT / 11AM PST

A separation of peptides is performed on a HALO 160 Å PCS C18 column showing excellent peak shape under formic acid conditions.

A separation of antidepressants is compared between a fully porous C18 and the HALO® PCS C18 column.

A synthetic peptide panel is screened on the HALO® Peptide PCS C18 and compared to a standard peptide C18 stationary phase.

Built upon Fused-Core® technology, the HALO® PCS C18 maintains peak symmetry at high loading capacities and provides alternate selectivity for C18 bonded phases.

The new HALO® PCS C18 phase offers an alternative to chromatographic separations.

In a head-to-head SPP comparison of two positively charged C18 surface chemistries, the HALO 90 Å PCS C18 obtains improved resolution, efficiency, and tailing factors.

Joseph Glajch, Ph.D., shares his expert perspective on the future of LC bio separations, hinting at the exciting possibilities that lie ahead for this transformative field.

In this episode of Trends in Modern Bio Separation Workflows brought to you by Advanced Materials Technology, Joseph Glajch Ph.D., President and Chief Consultant, JLP AP Consulting LLC,discusses how the landscape of bio separations has evolved, how monoclonal antibodies have dominated the market, the current challenges for research scientists and the tools available to them and lastly where he sees the future of LC bio separations.

Webinar Date/Time: Airing 1: Tuesday, February 28th, 2023 at 9am EST | 6am PST | 2pm GMT | 3pm CET Airing 2: Tuesday, February 28th, 2023 at 2pm EST | 11am PST | 7pm GMT | 8pm CET

Webinar Date/Time: Thu, Dec 8, 2022 2:00 PM EST

Thursday, November 3rd, 2022 Session 1: 10am EDT|7am PDT|3pm BST|4pm CEST Session 2: 2pm EDT|11am PDT|7pm BST|8pm CEST Want to increase the sensitivity of your UHPLC and LC–MS separations of peptides and proteins and save solvent without having to invest in a specialized microflow system? Learn how to achieve these goals with new 1.5 mm ID UHPLC columns packed with Fused-Core particles.

Thursday, September 15th, 2022 at 10am EDT|7am PDT|3pm BST|4pm CEST Thursday, September 15th, 2022 at 2pm EDT|11am PDT|7pm BST|8pm CEST Want to increase the sensitivity of your UHPLC and LC–MS separations of peptides and proteins and save solvent without having to invest in a specialized microflow system? Learn how to achieve these goals with new 1.5 mm ID UHPLC columns packed with Fused-Core particles.

Introducing a new dimension in separations! The new HALO® 1.5 mm ID UHPLC columns from Advanced Materials Technology push the performance of UHPLC systems by delivering more sensitivity and 50% less solvent consumption than contemporary 2.1 mm ID columns. Additional benefits of moving to the new, robust 1.5 mm ID columns will be discussed including the ease of implementation commercial UHPLC instrumentation.

Fused-Core® Technology benefits PFAS analysis for fast, efficient, and rugged separations which are paramount to environmental analysis.

HALO® PFAS and PFAS Delay columns are application verified columns well suited for challenging environmental sample analysis.

High resolution separation of 24 PFAS compounds using the HALO® PFAS Delay column coupled with the HALO® PFAS analytical column.

High throughput analysis of 33 PFAS compounds found across EPA methods 533, 537.1, and 8327 in under 5 minutes.

HALO® PFAS delay and HALO® PFAS analytical columns deliver rugged, reproducible performance for the most challenging environmental sample matrices.

Rapid and high-resolution analysis of PFAS compounds across EPA methods 537.1, 533, and 8327, using the new HALO® PFAS delay and analytical columns.

Europe: Tuesday, September 14, 2021 at 10am EDT | 3pm BST | 4pm CEST US: Tuesday, September 14, 2021 at 2pm EDT| 1pm CDT | 11am PDT Could your environmental and food safety LC and LC–MS separations be improved? Wish you had performance assurances before beginning your separations? Join us to learn how!

Wednesday, July 21, 2021 at 1pm EDT | 12pm CDT | 10am PDT In this webcast we address the fundamental concepts and tools that are key to developing optimized methods via reversed phase liquid chromatography (RPLC)—the most adopted and common mode of separation science. Providing both an understanding of visual models (modified Tanaka tests) and numerical models (HSM) and using application examples, separation scientist of all levels will leave with an understanding of how to develop better methods and the benefit of superficially porous particles.