James Sweatman holds a bachelor’s degree in chemistry from the University of Liverpool, UK, and a master’s degree in analytical chemistry from the University of Huddersfield, UK, and is currently an analytical investigator at Almac Sciences in Northern Ireland. With a career in analytical chemistry spanning over 28 years in the environmental and healthcare fields, he is an expert in analytical method development for small molecules with various chromatographic and spectroscopic techniques. Since joining Almac Sciences in 2007, he has led the analytical development and validation support for many small molecule GMP manufacturing campaigns. Direct correspondence to: james.sweatman@almacgroup.com
Overcoming Common Challenges to Determine Residual Impurities Using IC in APIs with Limited Water
December 10th 2024Organic solvents are generally not compatible with ion chromatography (IC) systems. The approach presented here assists the use of organic solvents for sample preparation and provides a mechanism for the removal of the organic solvents from the chromatographic flow path.