GC–MS

A novel isotopologue was synthesized in a stable isotope dilution assay (SIDA) for quantification of γ-nonalactone for the first time in pinot noir wines from New Zealand.

Enhancements in chromatographic performance were reviewed as were experimental concerns, both pointing toward using specific solvents to influence more sustainable industrial development.

Scientists have developed a novel sorbent, diphenyl-functionalized nickel foam (NF-2Ph), for the accurate detection of polycyclic aromatic hydrocarbon (PAH) contaminants in Chinese herbal medicines. The method, which combines dispersive solid-phase extraction (DSPE) with gas chromatography-mass spectrometry (GC–MS) analysis, offers high sensitivity and precision, providing a reliable approach for quality control and safety assessment of these medicinal products.

Gas chromatography coupled to mass spectrometry (GC–MS) has been the gold standard in this application, but its limitations in differentiating cancer subtypes have led to the exploration of newer related technologies.

A recent study reveals that pesticide residues in herbs have a low transfer rate to herbal infusions, ensuring safer consumption of these products. The validated analytical method used in the study provides valuable insights into the levels of pesticide residues in herbs and their limited presence in the resulting infusions.

In a talk at ASMS 2023, Stephanie Rankin-Turner of the Johns Hopkins Bloomberg School of Public Health detailed how thermal desorption–gas chromatography–mass spectrometry (TD–GC–MS) analyzed the body odor of humans to quantify mosquitos' attraction to them.

A new method for monitoring tricyclic antidepressants (TCA) in biological fluids and tissues in real time was proposed for the purposes of improving their effects or determining causes of death.

Extraction of gasoline and its major aromatic groups was promising using a carbon nanotube-assisted solid-phase microextraction (CNT-SPME) fiber.

We interviewed an AI program (ChatGPT) for LCGC North America asking questions about AI and its role in various applications for separation science to include data analysis, and high performance liquid chromatography (HPLC), hydrophilic-interaction chromatography (HILIC), reversed-phase liquid chromatography (RPLC), liquid chromatography–mass spectrometry (LC–MS), gas chromatography–mass spectrometry (GC–MS), high resolution mass spectrometry (HRIM–MS), high resolution tandem mass spectrometry (HRMS/MS), and related topics.

Webinar Date/Time: Thu, Jun 8, 2023 11:00 AM EDT

This month we interview Juan L. Benedé from the University of Valencia in Spain, about his work developing microextraction approaches, based on the use of sorbent materials, for application to complex matrices, and his focus on the determination of disease biomarkers in biofluids.

How to enhance the sensitivity, specificity, and speed of metabolite measurement using TIMS, which in turn helps to accelerate the pace of metabolomics research.

A solid-phase microextraction (SPME) Arrow combined with comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC–MS) identified about 40 more volatile compounds in a variety of whiskeys compared to conventional SPME.

The reliability of column chromatography for GC–MS analysis of hopanes was tested in oil samples of three different types, using neutral alumina as a solid-phase adsorbent and a Pasteur pipette as a separation device.

Researchers have used comprehensive two-dimensional gas chromatography with time of flight mass spectrometry and Fisher-ratio analysis to evaluate the breakdown of organic-based getters used to absorb gases and vapors from their surroundings.

High performance liquid chromatography–mass spectrometry and gas chromatography–mass spectrometry, along with numerous extraction methods, are helping to find organosulfur compounds in food more easily, providing researchers better information about the health benefits of these substances.

Exploring the impact of green chemistry on analytical chemistry and GC is the focus of this instalment of "GC Connections".

Direct-injection mass spectrometry (DIMS) and gas chromatography (GC) approaches have some significant differences that are pertinent when analyzing volatile organic compounds (VOCs). We explain.

Everyone is talking about sustainability, and organizations are creating sustainability programs. But what does green chemistry really mean, and how does it apply to gas chromatography?

Pesticides in local surface and groundwaters were purified and enriched with solid-phase extraction, then analyzed using multidimensional gas chromatography coupled to mass spectrometry, with the results compared to those found by gas chromatography–quadrupole mass spectrometry.

GC-MS technology has been used to study the inflammatory mechanism in COVID-19 patients, revealing the possible mechanism of inflammatory response in patients from the perspective of metabolomics.

A new study has demonstrated a practical solution for the reliable compound-specific isotope analysis (CSIA) of trace-level pollutants in complex environmental samples, using 2DGC-IRMS.

New GC–MS research suggests that the presence of hemicellulose impurities in α-cellulose extracted from land plants may compromise reliable application of the 18O/16O ratio for environmental, physiological, and metabolic studies.

While pesticides may be beneficial, they may also cause health risks in foods. In a recent study, scientists created new methods for detecting maximum pesticide residue levels.

A new differential ion mobility spectrometry device has been created that will greatly change how chemicals and substances are found and analyzed.

By performing tissue analysis of caracals in captivity and in their natural African habitats, scientists were able to quantify uptake of toxic chemicals from the environment depending on how polluted they are.

Using gas chromatography and mass spectrometry, a recent study was able to identify several compounds that give specialty coffee their fruity flavors and aromas.

"GC Connections" presents the column's annual review of new developments made in the field of gas chromatography, made available in 2022–2023.

Webinar Date/Time: Wednesday, April 26th, 2023 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST

The monitoring of per- and polyfluoroalkyl substances (PFAS) into food is an important environmental and health concern. Raquel Sendón García, PhD, is a Faculty Member in the Department of Analytical Chemistry of Nutrition and Food Science, and a Faculty of Pharmacy member at the University of Santiago de Compostela in Spain. She has been performing research on food contamination and the presence of potentially harmful chemicals in foods for some time. We recently spoke to her about her work using GC–MS and other analytical techniques to analyze PFAS migration into food from packaging materials.