Improving efficiency with EBA chromatography
November 9th 2009Richter-Helm BioLogics has announced that it will be improving the efficiency of its downstream processing capabilities by using 2nd Generation Expanded Bed Adsorption (EBA) chromatography that has been developed by the Danish company Upfront Chromatography.
Increased Efficiency and Resolution with Kinetex Core-Shell Technology
November 6th 2009The combination of the small particle size and narrow particle size distribution coupled with the significantly shorter diffusion path provided by the Kinetex™ core-shell particle results in a material that yields significantly increased column efficiencies and chromatographic resolution. This is a significant benefit for separation scientists looking to increase efficiency and chromatographic resolution, especially for complex separations containing many compounds and very closely eluting compounds so that accurate identification and quantitation can be achieved.
A Novel Sample Preperation Approach to Increase the Throughput of Pesticide Analysis by LC–MS–MS
November 1st 2009The high-throughput analysis of pesticides in raw agricultural commodities has been hindered by the slow and laborious sample preparation stages. Using traditional clean-up procedures, as many as 20 steps are required to get the sample in a convenient form for analysis, which typically limits sample throughput to eight samples per day. This study evaluates a new approach using a novel laboratory mill and pulverizer to extract various pesticide residues from different kinds of plant materials and to identify and quantify the active ingredients by liquid chromatography tandem mass spectrometry (LC–MS–MS). It shows that by automating the procedure, the number of clean-up steps can be reduced significantly, which increases sample throughput over traditional approaches.
Taking the Industry's Pulse After a Challenging 2009
November 1st 2009It seems hard to believe that we are already nearing the holidays and the end of 2009. And for many in the world of separation science, after weathering difficult economic conditions, solvent shortages, and more, welcoming in 2010 will be something to look forward to indeed.
Online SPE-LC analysis of aflatoxins — advances in sample preparation
October 30th 2009Sample preparation for instrumental analysis is of crucial importance to the quality of the test results as well as for the speed of the analysis. In liquid chromatography, SPE (solid phase extraction) is a widely used technique for concentrating analytes and for removal of matrix components.