Oxidative Metabolism of Acetaminophen Using ROXY EC System

Article

Acetaminophen (paracetamol; APAP; IUPAC: N-(4-hydroxyphenyl)acetamide) was chosen as model drug to investigate oxidative metabolism using the ROXY EC System dedicated for single component screening. Electrochemical conversion of the acetaminophen into reactive phase I metabolites and the NAPQI ? GSH phase II conjugate was successfully achieved.

External Link - article-659734.pdf

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