Gas Chromatography (GC)

This article examinations the determination of retention time and why it's important.

A recent study in the Journal of Forensic Science reveals a significant improvement in the identification of fentanyl-related substances by using GC–infrared (GC–IR) libraries to combat the opioid crisis.

Here are the top five articles that the editors of LCGC International published this week.

Adopted 35 years ago, the Montreal Protocol is an international treaty designed to protect the ozone layer. It addresses ozone depletion caused by industrial chemicals and remains a landmark environmental agreement in the phasing out and ban of the production and consumption of ozone-depleting substances (ODSs).

The 26th Norwegian Symposium on Chromatography was held 21–23 January 2024. The symposium has strong traditions in the Norwegian separation science community, serving as a forum for excellent scientific talks, networking, and social events.

A study has used gas chromatography coupled to a time-of-flight mass spectrometer to build an electron ionization mass spectra database of more than 250 chemicals classified as either volatile or semi-volatile compounds. An additional, confirmatory layer of liquid chromatography–mass spectrometry analysis was subsequently performed.

Element Materials Technology introduced its Rapid Response Pharmaceutical Testing Service, providing expedited testing and focusing on various requirements including active ingredients and final drug products, extractables and leachables, degradation production, and elemental impurities.

A study has proposed targeted methods, developed using gas chromatography coupled to tandem mass spectrometry, to measure human plasma protein binding and hepatocyte clearance in 73 per- and polyfluoroalkyl substances, or PFAS.

A recent review article highlights the current analytical techniques being used to detect illicit drug use in sports.

In this edition of “Inside the Laboratory,” Emanuela Gionfriddo, PhD, an associate professor of chemistry at the University at Buffalo, discusses her group’s current research endeavors, including using solid-phase microextraction (SPME) coupled to liquid chromatography (LC) and gas chromatography (GC) to further understand the chemical relationship between environmental exposure and disease and elucidate micropollutants fate in the environment and biological systems.

The company’s new service will provide expedited testing to customer around the world.

This week, LCGC International published a variety of articles on the hottest topics in chromatography and beyond. Below, we’ve highlighted some of the most popular articles, according to our readers. Happy reading!

In this edition of “Inside the Laboratory,” Kevin Schug, PhD, a full professor of chemistry at the University of Texas at Arlington, discusses his laboratory’s group work in environmental monitoring around water and soil quality near oil and gas extraction, using techniques such as liquid chromatography (LC), gas chromatography (GC), supercritical fluid chromatography (SFC), and coupling these techniques with mass spectrometry (MS).

Scientists investigated using this method to measure volatile organic compounds in the breath of patients with chronic kidney disease.

LCGC International sat down with John Luck, CCO, and Dirk Bontridder, CEO, of the instrument manufacturer PerkinElmer to discuss trends in the analytical and life sciences industry.

Researchers from Austria, Greece, and Italy conducted a study to analyze volatile organic compounds (VOCs) present in Irish and Scotch whiskys using solid-phase microextraction (SPME) Arrow with comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC–MS) to examine the organoleptic characteristics that influence the taste of spirits.

In this installment, we examine several of the common parameters that can affect automated peak integration and the resulting peak areas. We will consider how the data system detects the beginning and end of the peak, how it determines the peak maximum, how real peaks are differentiated from noise, and how signals at individual time intervals are summed to generate the peak area.

A group of Taiwanese scientists have recently created a new method for assessing food quality and detecting histamine in wine samples.

During a workshop at Pittcon, David Alonso of LECO Corporation discussed how gas chromatography–time-of-flight mass spectrometry (GC-TOFMS) can be used to identify polyfluorinated alkyl chemicals (PFAS) chemicals in anti-fog product solutions.

On February 25, a Pittcon oral session, titled “Detection of PFAS and other Polyfluorinated Analytes,” took place at the San Diego Convention Center in San Diego, California. This session included six talks that covered a variety of analytical techniques currently being used in per- and polyfluoralkyl (PFAS) analysis.

At Pittcon 2024, He Nan of AbbVie gave a lecture on how to monitor N-nitrosamines via gas chromatography–electron capture detection.

A new method has been developed to provide a sensitive, accurate and convenient GC–MS method to align with the new European regulation in relation to the introduction of the new Accutrace Plus marker for fuels.

The 18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology will take place from 28–31 May 2024 in Leuven, Belgium.

Blood and sputum are the most common means of detection by diagnostic tests, but producing adequate sputum can be difficult given a dry cough is often a TB symptom.

Researchers employed advanced chromatography and mass spectrometry techniques to unravel the chemical components and metabolites of Lingbao Huxin Dan, pinpointing its therapeutic potential for cardiovascular ailments.

Distinguishing between viable and non-viable seeds requires an advanced chromatographic technique. A study conducted by researchers from China Agricultural University highlights how HS-GC-IMS can be used to help solve this frequent problem in the agricultural industry.

A polydimethylsiloxane (PDMS) silicone rubber band sampler was used to collect volatile organic compounds (VOCs) from the skin of both tuberculosis (TB)-positive and TB-negative subjects.

Alicat™ Scientific releases the next generation of OEM flow controllers and meters.

Non-alcoholic beers are becoming more popular and need to reflect the sophisticated flavourings of beers that are brewed containing alcohol. Sophisticated analytical techniques can help to achieve this.

Scientists from the University of Calgary recently developed a novel method for externally adjusting the column length during gas chromatography (GC) operation.