Gas Chromatography (GC)

We interviewed an AI program (ChatGPT) for LCGC North America asking questions about AI and its role in various applications for separation science to include data analysis, and high performance liquid chromatography (HPLC), hydrophilic-interaction chromatography (HILIC), reversed-phase liquid chromatography (RPLC), liquid chromatography–mass spectrometry (LC–MS), gas chromatography–mass spectrometry (GC–MS), high resolution mass spectrometry (HRIM–MS), high resolution tandem mass spectrometry (HRMS/MS), and related topics.

A new methodology for trapping polycyclic aromatic hydrocarbons from vehicular emissions using an in-tube extraction device (IT-FEx) and analyzing them through gas chromatography-barrier ionization discharge detection (GC-BID) has been developed and tested successfully, according to a study published in the Journal of Chromatography A.

Manufacturing capillary gas chromatography (GC) columns is a very complex procedure, with many production factors to consider. In this LCGC Blog, Tony Taylor lists some of the vital components of the GC column-making process.

This month we interview Juan L. Benedé from the University of Valencia in Spain, about his work developing microextraction approaches, based on the use of sorbent materials, for application to complex matrices, and his focus on the determination of disease biomarkers in biofluids.

How to enhance the sensitivity, specificity, and speed of metabolite measurement using TIMS, which in turn helps to accelerate the pace of metabolomics research.

The workshop will take place 28–29 June 2023 in Liège, Belgium.

Researchers compared two widely used equations to identify pitfalls in normalizing specific retention volume for inverse gas chromatography (IGC) analysis.

A solid-phase microextraction (SPME) Arrow combined with comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC–MS) identified about 40 more volatile compounds in a variety of whiskeys compared to conventional SPME.

The reliability of column chromatography for GC–MS analysis of hopanes was tested in oil samples of three different types, using neutral alumina as a solid-phase adsorbent and a Pasteur pipette as a separation device.

Researchers have used comprehensive two-dimensional gas chromatography with time of flight mass spectrometry and Fisher-ratio analysis to evaluate the breakdown of organic-based getters used to absorb gases and vapors from their surroundings.

The level of uncertainty provided by most forensic laboratories for reported blood alcohol results has been woefully underassessed. Not only is this bad science, but someone’s civil liberties may be at stake.

High performance liquid chromatography–mass spectrometry and gas chromatography–mass spectrometry, along with numerous extraction methods, are helping to find organosulfur compounds in food more easily, providing researchers better information about the health benefits of these substances.

Exploring the impact of green chemistry on analytical chemistry and GC is the focus of this instalment of "GC Connections".

Limitations often arise when using GC with quadrupole-based mass spectrometers for detecting volatile and semivolatile contaminants. Enter HRAMS-MS.

Direct-injection mass spectrometry (DIMS) and gas chromatography (GC) approaches have some significant differences that are pertinent when analyzing volatile organic compounds (VOCs). We explain.

Everyone is talking about sustainability, and organizations are creating sustainability programs. But what does green chemistry really mean, and how does it apply to gas chromatography?

By following some simple guidelines, you can ensure your GC columns live a long and healthy life.

Pesticides in local surface and groundwaters were purified and enriched with solid-phase extraction, then analyzed using multidimensional gas chromatography coupled to mass spectrometry, with the results compared to those found by gas chromatography–quadrupole mass spectrometry.

A new study has demonstrated a practical solution for the reliable compound-specific isotope analysis (CSIA) of trace-level pollutants in complex environmental samples, using 2DGC-IRMS.

New GC–MS research suggests that the presence of hemicellulose impurities in α-cellulose extracted from land plants may compromise reliable application of the 18O/16O ratio for environmental, physiological, and metabolic studies.

Webinar Date/Time: Monday, May 22nd, 2023 Morning Session: 9am EDT | 6am PDT | 2pm BST | 3pm CEST Lunchtime Session: 1pm EDT | 10am PDT | 6pm BST | 7pm CEST Afternoon Session: 2pm EDT | 11am PDT | 7pm BST | 8pm CEST Tuesday, May 23rd, 2023 Morning Session: 9am EDT | 6am PDT | 2pm BST | 3pm CEST Lunchtime Session: 1pm EDT | 10am PDT | 6pm BST | 7pm CEST Afternoon Session: 2pm EDT | 11am PDT | 7pm BST | 8pm CEST

While pesticides may be beneficial, they may also cause health risks in foods. In a recent study, scientists created new methods for detecting maximum pesticide residue levels.

A new differential ion mobility spectrometry device has been created that will greatly change how chemicals and substances are found and analyzed.

By performing tissue analysis of caracals in captivity and in their natural African habitats, scientists were able to quantify uptake of toxic chemicals from the environment depending on how polluted they are.

Using gas chromatography and mass spectrometry, a recent study was able to identify several compounds that give specialty coffee their fruity flavors and aromas.

We assess the landscape of new gas chromatography (GC) instrumentation, supplies, and accessories introduced over the past 12 months.

LCGC Europe spoke to Giorgia Purcaro from the University of Liège in Belgium, about her work investigating mineral oil hydrocarbons (MOH) using GCxGC and the practical advantages that a novel LC–GCxGC–TOF-MS/FID method offers the analyst.

"GC Connections" presents the column's annual review of new developments made in the field of gas chromatography, made available in 2022–2023.

The 20th International GC×GC Symposium will take place from 28 May–1 June 2023, and will be held in Canmore, Alberta.

The 2nd "Advances in Separation Science: From Extraction to Chromatographic Applications" workshop will be held from 28–29 June 2023 in the University of Liège in Belgium.