Gas Chromatography (GC)

As part of our ISC 2024 coverage, we recently interviewed Caitlin Cain of the University of Michigan about her scientific background and her thoughts on winning our Rising Stars of Separation Science Award for Gas Chromatography.

Caitlin Cain has developed one-dimensional and comprehensive two-dimensional gas chromatographic methods using novel data analysis approaches.

A morning session at the International Symposium on Chromatography in Liverpool presented analytical challenges and potential solutions for PFAS analysis, oil pollution, and microplastics.

The 34th International Symposium on Chromatography kicked off on October 6 in Liverpool, featuring two plenary sessions and an opening ceremony.

Here is some of the most popular content posted on LCGC International this week.

ETHZ and Agroscope scientists tested a new means of analysis against secondary electrospray ionization (SESI) coupled to high-resolution-mass spectrometry (HRMS) for exhaled breath analysis.

Here is some of the most popular content posted on LCGC International this week.

Posters at the 2024 conference will feature research on a variety of topics from PFAS testing to the HPLC analysis of soft drinks.

The 2024 Gulf Coast Conference will include a variety of presentations on chromatography. This article features a sampling of some upcoming sessions.

Shangdong University and Shandong Energy Group scientists recently used HS-GC-IMS was used alongside machine learning algorithms to detect the geographic origins of coal associated with larceny cases.

Here is some of the most popular content posted on LCGC International this week.

For trace quantitative analysis, the splitless technique is most used as an inlet capable of performing both split and splitless injections. In this and upcoming installments, we take a closer look at splitless injection.

The introduction of comprehensive two-dimensional gas chromatography (GC×GC) to the sample screening toolbox has substantially increased the ability to comprehensively characterize complex mixtures. However, for many gas chromatography (GC) users, the thought of having to learn to develop methods on a new technology is daunting. Developing a basic GC×GC method for most (nonspecialized) applications can be accomplished in minimal time and effort given parameter suggestions and ranges to target analytes in a sample of interest. In this article, the authors work describe a simple workflow to develop a GC×GC method for a specific sample upon initial use, with the aim of decreasing the time to accomplish functional workflows for new users.

Column insertion distance is critical to good chromatography. What happens if the column is installed too low in the injection port? Is insertion distance more important when performing split injection or splitless injection? Does the position of the column in the injection port impact reproducibility?

University of Bonn scientists monitored how column properties can affect the dynamics between characteristic and elution temperatures in gas chromatography (GC).

In this LCGC Blog, Daipayan Roy and Muhammed Qamar Farooq of Amgen discuss the history and impact of supercritical fluid chromatography (SFC) throughout the years.

Here are the top five articles published on LCGC International this week.

A recent study analyzed nearly 100 CBD products to test the accuracy of advertised cannabinoid content.

Scientists from Shanghai Jiao Tong University and the Sichuan China Tobacco Industry Company used gas chromatography-ion mobility spectrometry (GC-IMS) to analyze the flavor profiles of different cigars.

Scientists from the Federal University of Santa Catarina reviewed recent advancements made in the chromatographic analysis of endocannabinoids and phytocannabinoids in biological samples.

Here are the top five articles published on LCGC International this week.

Connecticut Agricultural Experiment Station scientists recently used gas chromatography with flame ionization detection (GC-FID) to measure different components in cannabis hemp samples.

University of Messina scientists recently used GC-based techniques to help characterize essential oil from Piper gaudichaudianum Kunth, a plant native to Brazil.

In this article, we discuss the fundamentals of headspace extraction, including static versus dynamic extraction, establishing equilibrium in the vial, consequences of the partition coefficient, temperature, pressure, and transfer to the gas chromatograph.

Pharmaceutical excipients, such as polyethylene glycol-based polymers, must be tested for the presence of ethylene oxide (EtO) and 1,4-dioxane as part of a safety assessment, according to USP Chapter <228>.

Mankind Research Centre scientists recently tested a new solid phase extraction (SPE)-based approach coupled with GC–MS for analyzing small molecule N–nitrosamine impurities in antitussive syrups.

São Paolo State University scientists recently used pyrolysis gas-chromatography–mass spectrometry and dispersive liquid-liquid microextraction to determine flame retardants in sewage.

Here are the top five articles published on LCGC International this week.

University of Campinas and Iowa State University scientists recently combined vacuum-assisted sorbent extraction (VASE) and gas chromatography-mass spectrometry (GC–MS) to determine polycyclic aromatic hydrocarbons in açaí-based food products.