April 1st 2025
In this edition of the LCGC Blog, Amber Hupp of the College of the Holy Cross reflects on her childhood and talks about her journey recreating the scents from that long past.
Study Reveals Low Transfer of Pesticide Residues from Herbs to Infusions
June 30th 2023A recent study reveals that pesticide residues in herbs have a low transfer rate to herbal infusions, ensuring safer consumption of these products. The validated analytical method used in the study provides valuable insights into the levels of pesticide residues in herbs and their limited presence in the resulting infusions.
Revolutionizing Atmospheric Monitoring: Hourly Tracking of Krypton-85 with Online Analysis
June 12th 2023A temperature-controlled cryogenic distillation and gas chromatography, atom trap measurement system is used for precise analysis of atmospheric 85Kr abundance. This advanced technology enables online monitoring with high sensitivity and reduced sample size requirements.
Exploring Mosquito Olfactory Preferences with Whole Body Volatilomics
June 7th 2023In a talk at ASMS 2023, Stephanie Rankin-Turner of the Johns Hopkins Bloomberg School of Public Health detailed how thermal desorption–gas chromatography–mass spectrometry (TD–GC–MS) analyzed the body odor of humans to quantify mosquitos' attraction to them.
An Interview with AI About Its Potential Role in Separation Science
May 17th 2023We interviewed an AI program (ChatGPT) for LCGC North America asking questions about AI and its role in various applications for separation science to include data analysis, and high performance liquid chromatography (HPLC), hydrophilic-interaction chromatography (HILIC), reversed-phase liquid chromatography (RPLC), liquid chromatography–mass spectrometry (LC–MS), gas chromatography–mass spectrometry (GC–MS), high resolution mass spectrometry (HRIM–MS), high resolution tandem mass spectrometry (HRMS/MS), and related topics.
New Device Developed to Detect Pollutants in Vehicle Emissions
May 15th 2023A new methodology for trapping polycyclic aromatic hydrocarbons from vehicular emissions using an in-tube extraction device (IT-FEx) and analyzing them through gas chromatography-barrier ionization discharge detection (GC-BID) has been developed and tested successfully, according to a study published in the Journal of Chromatography A.
Rising Stars of Separation Science: Juan L. Benedé
May 9th 2023This month we interview Juan L. Benedé from the University of Valencia in Spain, about his work developing microextraction approaches, based on the use of sorbent materials, for application to complex matrices, and his focus on the determination of disease biomarkers in biofluids.
SPME Arrow Improves Upon Conventional SPME in GC×GC–MS Analysis of Whiskey Flavor Compounds
May 5th 2023A solid-phase microextraction (SPME) Arrow combined with comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC–MS) identified about 40 more volatile compounds in a variety of whiskeys compared to conventional SPME.
GC✕GC–TOF-MS Used with F-ratio Analysis to Evaluate Volatiles in Getter Substrate Breakdown
May 2nd 2023Researchers have used comprehensive two-dimensional gas chromatography with time of flight mass spectrometry and Fisher-ratio analysis to evaluate the breakdown of organic-based getters used to absorb gases and vapors from their surroundings.
The LCGC Blog: Forensics Laboratories Underassess Uncertainty in Blood Alcohol Determinations
May 2nd 2023The level of uncertainty provided by most forensic laboratories for reported blood alcohol results has been woefully underassessed. Not only is this bad science, but someone’s civil liberties may be at stake.
Using HPLC–MS and GC–MS for Improving Speed and Accuracy of Organosulfur Compound Detection
May 2nd 2023High performance liquid chromatography–mass spectrometry and gas chromatography–mass spectrometry, along with numerous extraction methods, are helping to find organosulfur compounds in food more easily, providing researchers better information about the health benefits of these substances.
Demystifying Sample Preparation for Headspace Analysis Using Direct Injection Mass Spectrometry
May 1st 2023Direct-injection mass spectrometry (DIMS) and gas chromatography (GC) approaches have some significant differences that are pertinent when analyzing volatile organic compounds (VOCs). We explain.
GC✕GC–TOF-MS Helps Quantify Pesticides in Water Susceptible to Contamination
April 28th 2023Pesticides in local surface and groundwaters were purified and enriched with solid-phase extraction, then analyzed using multidimensional gas chromatography coupled to mass spectrometry, with the results compared to those found by gas chromatography–quadrupole mass spectrometry.