Fast Analysis of "Dirty" Samples with Monolithic Silica LC and Silica Gel TLC Stationary Phases
July 1st 2014The development of fast and straightforward processes of sample preparation, separation, and detection for the analysis of various food and pharmaceutical samples with a high matrix load are described.
Radical Mass Spectrometry as a New Frontier for Bioanalysis
July 1st 2014In this article, we discuss radical MS, an increasingly important area of MS development and the application to bioanalysis. At the current stage, most of the research is performed by a small set of academic groups; it is likely that these types of fundamental studies will attract more attention and even be commercialized in the near future.
Analysis of Wastewater in New York State Indicates Illicit Drug Consumption
June 23rd 2014The study of sewage using chromatographic techniques is a rapidly expanding area that can provide insights into the consumption of illicit drugs. Measuring illicit drug concentrations can provide authorities with a close to real time identification of consumption trends and rates in specific geographical areas.
Ultra-Fast Analysis of Alkaloids and Permitted Additives in Dark Chocolate Products
June 19th 2014A simple, rapid, and robust UHPLC method for the simultaneous determination of polyphenols, methylxanthines, sweeteners, and flavouring substances as well as some common preservatives has been developed using an automated method scouting and method optimization workflow.
The LCGC Blog: A Report from Riva del Garda: The Current State of the Art of Gas Chromatography
June 19th 2014The International Symposium on Capillary Chromatography (ISCC) and GCxGC Symposium combined conference provides an excellent combination of high impact, cutting edge science, and a great social program in an interesting venue. Kevin Schug shares his thoughts about innovations in gas chromatography presented at this year's conference in Riva del Garda, Italy.
Profiling MDMA Impurities Using HS–SPME
June 19th 2014Profiling impurities in MDMA (also known as ecstasy) is essential to forensic science as different profiles can provide clues about the source. Two researchers from Michigan State University (Michigan, USA) investigated the effect of liquid–liquid extraction (LLE), headspace solid-phase microextraction (HS–SPME), and different gas chromatography temperature programmes highlighting the need for standardized procedures.
New LC–MS–MS Method to Detect Counterfeit Drugs
June 19th 2014Researchers at the Universite de Montreal in Canada have developed and validated a new liquid chromatography tandem mass spectrometry (LC–MS–MS) method to identify compounds present in suspected counterfeit or even adulterated erectile dysfunction drugs. According to the study published in the Journal of Chromatography A, the method has now been introduced to the Inspectorate Laboratory Programme at Health Canada (Canada).