All News

Both the volume of the sample injection and the solvent in which the sample is dissolved can affect the appearance of the chromatogram.

Professor Wolfgang Lindner spoke to Kevin A. Schug about his inspiring and influential career in chromatography.

The quantification of proteins in a complex biological sample is an important and challenging task. Mass spectrometry (MS) is increasingly used for this purpose, not only to give a global survey of the components and their amounts, but also to precisely and accurately quantify specific target proteins.

Confidential 2015 New Gas Chromatographs, Systems and Accessories Introduction Information

In this article, two sample handling and sample preparation methods for saliva samples are presented and discussed. Both methods were applied for determining the presence of lidocaine in saliva.

We recently spoke to Gary Duncan and Wendy Russell of the Rowett Institute of Nutrition & Health in Aberdeen, Scotland, about the significance of phytochemical bioavailability to human health and the important role of liquid chromatography linked to tandem mass spectrometry (LC–MS-MS) in their research.

How to spot weaknesses in methods before problems occur

A new, single method to replace the two-method approach using EPA methods TO-15 and TO-13A to analyze both volatile and semivolatile organic compounds in air.

Click the title above to open the LCGC Europe October 2014 regular issue, Vol 27, No 10, in an interactive PDF format.

Click the title above to open the LCGC North America October 2014 regular issue, Vol 32 No 10, in an interactive PDF format.

Click the title above to open the October 2014 issue of Current Trends in Mass Spectrometry, Volume 12, Number 4, in an interactive PDF format.

Click here to view the complete E-separation Solutions newsletter from September 30, 2014.

Whether your GC instrument has been shut down for a couple of days or been sat gathering dust in a corner for a year, follow our quick checklist to get you up and running.

Waters Corporation (Massachusetts, USA) has opened a new custom-built mass spectrometry headquarters in Wilmslow, UK. The new headquarters took less than two years to construct from the initial ground breaking to completion, and brings together existing centres in the region consisting of more than 500 employees.

The LCGC Europe news update from September 25 2014.

Waters Corporation (Massachusetts, USA) has opened a new custom-built mass spectrometry headquarters in Wilmslow, UK. The new headquarters took less than two years to construct from the initial ground breaking to completion, and brings together existing centres in the region consisting of more than 500 employees.

Fast GC

Scientists in Vietnam have performed high?resolution gas chromatography coupled with high-resolution mass spectrometry (HRGC?HRMS) analysis of breast milk to determine the level of dioxin and furan exposure around the Da Nang Agent Orange hotspot in Vietnam.1 Agent Orange contamination is associated with elevated and persistent levels of dioxins and furans in the environment and are associated with the occurrence of birth defects among other side effects.

Merck KGaA (Darmstadt, Germany) has announced that it has entered into an agreement to acquire Sigma-Aldrich (Kansas City, Missouri, USA) for approximately $17 billion (€13.1 billion).

The World of Technology & Science 2014 (WOTS) exhibition will be held between 30 September and 3 October 2014 at the Jaarbeurs Exhibition and Conference Centre, Utrecht, The Netherlands, organized by two collaborating Dutch associations, FHI (Federation of Technology Branches) and FEDA.

This review discusses recent technological advances in classical heart-cuttting two-dimensional gas chromatography (GC–GC). These developments are then illustrated by application to analysis of important flavour compounds at trace levels in very complex matrices

Incognito believes in the power of creative thinking to solve problems in the analytical laboratory. Do you think creatively?

Scientists in Vietnam have performed high-resolution gas chromatography coupled with high-resolution mass spectrometry (HRGC–HRMS) analysis of breast milk to determine the level of dioxin and furan exposure around the Da Nang Agent Orange hotspot in Vietnam. Agent Orange contamination is associated with elevated and persistent levels of dioxins and furans in the environment and are associated with the occurrence of birth defects among other side effects.

Waterpipes have been used to smoke tobacco and other substances for more than four centuries, and are widely believed to be less harmful than cigarettes. In a new study published in the journal Science of the Total Environment, gas chromatography coupled to mass spectrometry (GC–MS–MS) was performed to show that waterpipe smoke can contain potentially harmful microbial compounds.

A team of scientists based in the Czech Republic has developed a micellular electrokinetic chromatography method coupled with tandem mass spectrometry (MEKC–ESI–MS–MS) that uses salts of perfluorocarboylic acid as the volatile background electrolyte (BGE). The method was applied to the determination of 12 drugs from the class of synthetic cathinones in urine samples. According to the paper published in the Journal of Chromatography A, the BGE used to form micelles did not affect the electron ionization efficiency of MS. (1)

An excerpt from LCGC's e-learning tutorial on critical evaluation of HPLC methods at CHROMacademy.com

The LCGC Europe news update from September 18 2014.

Click the title above to open The Column September 18, 2014 North American issue, Volume 10, Number 17, in an interactive PDF format.

Click the title above to open The Column September 18, 2014 Europe & Asia issue, Volume 10, Number 17, in an interactive PDF format.

Most of us who have used UV detection for HPLC analyses consider them very straightforward and find they produce fit for purpose data whenever we need them to.