All News

Click the title above to open The Column July 24, 2014 North American issue, Volume 10, Number 13, in an interactive PDF format.

Click the title above to open The Column July 24, 2014 Europe & Asia issue, Volume 10, Number 13, in an interactive PDF format.

Deirdre Cabooter from KU Leuven (Belgium) describes how to use the variable length method development strategy to develop successful UHPLC methods and how this approach can save time for the analyst.

LCGC spoke to Gary Duncan and Wendy Russell of the Rowett Institute of Nutrition & Health in Aberdeen, Scotland, about the significance of phytochemical bioavailability to human health and the important role of liquid chromatography linked to tandem liquid chromatography mass spectrometry (LC-MS-MS) in their research.

Phenomenex Inc. (Torrance, California, USA) has revealed it will be launching a spin-off company focusing on biological sampling called Neoteryx LLC.

We all have always been told that we need to listen, and to listen more carefully. Growing up, we were told to listen to our parents and our teachers. But have you considered listening to your analytical instruments?

Much has been written about column overload, however, I've seen many instances lately in which overload may not be instantly recognized, or causes problems that may not normally be attributed to overload. Therefore, I wanted to explain how to spot and deal with different types of overload situations.

Click here to view the complete E-Separation Solutions newsletter from July 17, 2014.

Waters Corporation (Milford, Massachusetts) entered into an agreement with the Chinese Pharmacopoeia Commission (ChP) to establish a joint open laboratory.

Click here to view the complete E-Separation Solutions newsletter from July 10, 2014.

The LCGC Europe news update from July 10 2014.

If you ask scientists, it does not take long before you realize that there is quite a bit of variety in the different search engines that they prefer.

Leaks in GC–MS are particularly insidious. How do you know when you have a leak and where do you start to look for it. It is something that will happen to all chromatographers at some point. Here is our quick guide to how to identify the source of GC–MS leaks.

App of the month: GPC Glossary

Waters Corporation and PSS GmbH have announced the return of the International GPC/SEC Symposium to be held at The Westin Grand Frankfurt Hotel in Frankfurt, Germany, on 30 September–2 October 2014.

Thirty percent of approved drugs will be based on recombinant monoclonal antibody (rMab) drugs over the next 10 years. Glycosylation, the convalent addition of carbohydrates to proteins, can influence properties of rMab drugs and has to be closely monitored during drug development and production. Scientists from the University of California (California, USA) have developed a new liquid chromatography–mass spectrometry (LC–MS) N-glycan library based on eight commercially available recombinant monoclonal antibodies, for the rapid identification of glycosylated structures.

Scientists from Emory University (Georgia, USA) have developed a new solid–phase extraction (SPE) method to isolate four insecticide degradates from baby food for analysis by high performance liquid chromatography tandem mass spectrometry (HPLC–MS–MS). The paper published in the Journal of Agricultural and Food Chemistry describes how the method can be applied to differentiate between exposure to insecticides or preformed degradates.

The study of sewage using chromatographic techniques is a rapidly expanding area that can provide insights into the consumption of illicit drugs. Measuring illicit drug concentrations can provide authorities with a close to real time identification of consumption trends and rates in specific geographical areas.

This article presents a method that combines combustion digestion and ion chromatography into a single analysis (combustion ion chromatography [CIC]) making it possible to detect halogens and sulphur in complex matrices. The method is suitable for use in a wide range of application areas.

An excerpt from LCGC's e-learning tutorial on HPLC problems at CHROMacademy.com.

Click the title above to open The Column July 07, 2014 North American issue, Volume 10, Number 12, in an interactive PDF format.

Click the title above to open The Column July 07, 2014 Europe & Asia issue, Volume 10, Number 12, in an interactive PDF format.

In the first video update to LCGC TV of 2015, Gérard Hopfgartner from the University of Geneva, University of Lausanne, Switzerland, discusses the advances in ion mobility mass spectrometry, highlighting the benefits of the technique and how it can be hyphenated to both 1D and 2D LC.

The LCGC Europe news update from July 3 2014.

Wyatt Technology Corporation

Malvern Instruments Ltd.

Safe and effective gas cylinder setup and use requires the right pressure regulators, fittings, tubing, and filters as well as careful attention to procedure. This month's instalment reviews how to get the best results from laboratory gas cylinders, how pressure regulators work, and what filters should be installed in gas lines.

This year's symposium was held in New Orleans, Louisiana, USA. In this review, Ron Majors covers HPLC and UHPLC column and sample preparation highlights, summarizes the awards presented, and reviews the overall liquid-phase chromatographic trends.

A review of Professor Barry L. Karger's years as a teacher and mentor, as well as his many scientific accomplishments

Events